Research output per year
Research output per year
- 10 results
Search results
-
2025
Generation of human fetal brain organoids and their CRISPR engineering for brain tumor modeling
Pagliaro, A., Andreatta, F., Finger, R., Artegiani, B. & Hendriks, D., 6 Feb 2025, (E-pub ahead of print) In: Nature protocols.Research output: Contribution to journal › Article › peer-review
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2024
Human fetal brain self-organizes into long-term expanding organoids
Hendriks, D., Pagliaro, A., Andreatta, F., Ma, Z., van Giessen, J., Massalini, S., López-Iglesias, C., van Son, G. J. F., DeMartino, J., Damen, J. M. A., Zoutendijk, I., Staliarova, N., Bredenoord, A. L., Holstege, F. C. P., Peters, P. J., Margaritis, T., Chuva de Sousa Lopes, S., Wu, W., Clevers, H. & Artegiani, B., Jan 2024, In: Cell. 187, 3, p. 712-732.e38Research output: Contribution to journal › Article › peer-review
Open Access -
Mapping of mitogen and metabolic sensitivity in organoids defines requirements for human hepatocyte growth
Hendriks, D., Artegiani, B., Margaritis, T., Zoutendijk, I., Chuva de Sousa Lopes, S. & Clevers, H., 13 May 2024, In: Nature communications. 15, 1, p. 4034Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Engineered human hepatocyte organoids enable CRISPR-based target discovery and drug screening for steatosis
Hendriks, D., Brouwers, J. F., Hamer, K., Geurts, M. H., Luciana, L., Massalini, S., López-Iglesias, C., Peters, P. J., Rodríguez-Colman, M. J., Chuva de Sousa Lopes, S., Artegiani, B. & Clevers, H., 2023, In: Nature biotechnology. 41, 11, p. 1567-1581 15 p.Research output: Contribution to journal › Article › peer-review
Open Access -
One-step generation of tumor models by base editor multiplexing in adult stem cell-derived organoids
Geurts, M. H., Gandhi, S., Boretto, M. G., Akkerman, N., Derks, L. L. M., van Son, G., Celotti, M., Harshuk-Shabso, S., Peci, F., Begthel, H., Hendriks, D., Schürmann, P., Andersson-Rolf, A., Chuva de Sousa Lopes, S. M., van Es, J. H., van Boxtel, R. & Clevers, H., 17 Aug 2023, In: Nature communications. 14, 1, p. 4998Research output: Contribution to journal › Article › peer-review
Open Access -
Organoid models of fibrolamellar carcinoma mutations reveal hepatocyte transdifferentiation through cooperative BAP1 and PRKAR2A loss
Rüland, L., Andreatta, F., Massalini, S., Chuva de Sousa Lopes, S., Clevers, H., Hendriks, D. & Artegiani, B., Jan 2023, In: Nature communications. 14, 1, p. 2377Research output: Contribution to journal › Article › peer-review
Open Access -
Temporal morphogen gradient-driven neural induction shapes single expanded neuroepithelium brain organoids with enhanced cortical identity
Pagliaro, A., Finger, R., Zoutendijk, I., Bunschuh, S., Clevers, H., Hendriks, D. & Artegiani, B., 28 Nov 2023, In: Nature communications. 14, 1, p. 7361Research output: Contribution to journal › Article › peer-review
Open Access -
2022
A comprehensive transcriptomic comparison of hepatocyte model systems improves selection of models for experimental use
Ardisasmita, A. I., Schene, I. F., Joore, I. P., Kok, G., Hendriks, D., Artegiani, B., Mokry, M., Nieuwenhuis, E. E. S. & Fuchs, S. A., 14 Oct 2022, In: Communications Biology. 5, 1, p. 1094 1094.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus) -
Multispectral confocal 3D imaging of intact healthy and tumor tissue using mLSR-3D
van Ineveld, R. L., Collot, R., Román, M. B., Pagliaro, A., Bessler, N., Ariese, H. C. R., Kleinnijenhuis, M., Kool, M., Alieva, M., Chuva de Sousa Lopes, S. M., Wehrens, E. J. & Rios, A. C., Dec 2022, In: Nature Protocols. 17, 12, p. 3028-3055 28 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
2021
Establishment of human fetal hepatocyte organoids and CRISPR-Cas9-based gene knockin and knockout in organoid cultures from human liver
Hendriks, D., Artegiani, B., Hu, H., Chuva de Sousa Lopes, S. & Clevers, H., Jan 2021, In: Nature protocols. 16, 1, p. 182-217 36 p.Research output: Contribution to journal › Article › peer-review
112 Citations (Scopus)