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  • 2018

    Anti-GD2 Immunoliposomes for Targeted Delivery of the Survivin Inhibitor Sepantronium Bromide (YM155) to Neuroblastoma Tumor Cells

    Gholizadeh, S., Dolman, E. M., Wieriks, R., Sparidans, R. W., Hennink, W. E. & Kok, R. J., 1 Apr 2018, In: Pharmaceutical Research. 35, 4, 85.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    26 Citations (Scopus)

  • RAS-MAPK Pathway-Driven Tumor Progression Is Associated with Loss of CIC and Other Genomic Aberrations in Neuroblastoma

    Eleveld, T. F., Schild, L., Koster, J., Zwijnenburg, D. A., Alles, L. K., Ebus, M. E., Volckmann, R., Tijtgat, G. A., van Sluis, P., Versteeg, R. & Molenaar, J. J., 1 Nov 2018, In: Cancer research. 78, 21, p. 6297-6307 11 p.

    Research output: Contribution to journal › Article › peer-review

    45 Citations (Scopus)

  • TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets

    Decaesteker, B., Denecker, G., Van Neste, C., Dolman, E. M., Van Loocke, W., Gartlgruber, M., Nunes, C., De Vloed, F., Depuydt, P., Verboom, K., Rombaut, D., Loontiens, S., De Wyn, J., Kholosy, W. M., Koopmans, B., Essing, A. H. W., Herrmann, C., Dreidax, D., Durinck, K. & Deforce, D. & 13 others, van Nieuwerburgh, F., Henssen, A., Versteeg, R., Boeva, V., Schleiermacher, G., van Nes, J., Mestdagh, P., Vanhauwaert, S., Schulte, J. H., Westermann, F., Molenaar, J. J., De Preter, K. & Speleman, F., 1 Dec 2018, In: Nature Communications. 9, 1, 4866.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    72 Citations (Scopus)

  • The landscape of genomic alterations across childhood cancers

    Gröbner, S. N., Worst, B. C., Weischenfeldt, J., Buchhalter, I., Kleinheinz, K., Rudneva, V. A., Johann, P. D., Balasubramanian, G. P., Segura-Wang, M., Brabetz, S., Bender, S., Hutter, B., Sturm, D., Pfaff, E., Hübschmann, D., Zipprich, G., Heinold, M., Eils, J., Lawerenz, C. & Erkek, S. & 64 others, Lambo, S., Waszak, S., Blattmann, C., Borkhardt, A., Kuhlen, M., Eggert, A., Fulda, S., Gessler, M., Wegert, J., Kappler, R., Baumhoer, D., Burdach, S., Kirschner-Schwabe, R., Kontny, U., Kulozik, A. E., Lohmann, D., Hettmer, S., Eckert, C., Bielack, S., Nathrath, M., Niemeyer, C., Richter, G. H., Schulte, J., Siebert, R., Westermann, F., Molenaar, J. J., Vassal, G., Witt, H., Zapatka, M., Burkhardt, B., Kratz, C. P., Witt, O., Tilburg, C. M. V., Kramm, C. M., Fleischhack, G., Dirksen, U., Rutkowski, S., Frühwald, M., Hoff, K. V., Wolf, S., Klingebiel, T., Koscielniak, E., Landgraf, P., Koster, J., Resnick, A. C., Zhang, J., Liu, Y., Zhou, X., Waanders, A. J., Zwijnenburg, D. A., Raman, P., Brors, B., Weber, U. D., Northcott, P. A., Pajtler, K. W., Kool, M., Piro, R. M., Korbel, J. O., Schlesner, M., Eils, R., Jones, D. T. W., Lichter, P., Chavez, L. & Pfister, S. M., 15 Mar 2018, In: Nature. 555, 7696, p. 321-327 7 p.

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1066 Citations (Scopus)
  • 2017

    Enhancer of zeste homologue 2 plays an important role in neuroblastoma cell survival independent of its histone methyltransferase activity

    Bate-Eya, L. T., Gierman, H. J., Ebus, M. E., Koster, J., Caron, H. N., Versteeg, R., Dolman, M. E. M. & Molenaar, J. J., 1 Apr 2017, In: European Journal of Cancer. 75, p. 63-72 10 p.

    Research output: Contribution to journal › Article › peer-review

    26 Citations (Scopus)

  • Neuroblastoma is composed of two super-enhancer-associated differentiation states

    Van Groningen, T., Koster, J., Valentijn, L. J., Zwijnenburg, D. A., Akogul, N., Hasselt, N. E., Broekmans, M., Haneveld, F., Nowakowska, N. E., Bras, J., Van Noesel, C. J. M., Jongejan, A., Van Kampen, A. H., Koster, L., Baas, F., Van Dijk-Kerkhoven, L., Huizer-Smit, M., Lecca, M. C., Chan, A. & Lakeman, A. & 11 others, Molenaar, P., Volckmann, R., Westerhout, E. M., Hamdi, M., Van Sluis, P. G., Ebus, M. E., Molenaar, J. J., Tytgat, G. A., Westerman, B. A., Van Nes, J. & Versteeg, R., 1 Aug 2017, In: Nature Genetics. 49, 8, p. 1261-1266 6 p.

    Research output: Contribution to journal › Article › peer-review

    351 Citations (Scopus)