Personal profile
Research interests
Onderzoeksbelangen
Education/Academic qualification
PhD, Preclinical development of biology-based therapeutic strategies for aggressive pediatric brain tumors, Vrije Universiteit Medical Center
Award Date: 5 Oct 2020
Master, MD, Vrije Universiteit Medical Center
Award Date: 27 Sept 2013
External positions
Resident in pediatrics, Wilhelmina Children's Hospital UMC
1 Feb 2021 → …
Keywords
- RJ101 Child Health. Child health services
- RC0254 Neoplasms. Tumors. Oncology (including Cancer)
- RM Therapeutics. Pharmacology
- QP Physiology
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Collaborations and top research areas from the last five years
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Gemcitabine therapeutically disrupts essential SIRT1-mediated p53 repression in atypical teratoid/rhabdoid tumors
Metselaar, D. S., Meel, M. H., Goulding, J. R., du Chatinier, A., Rigamonti, L., Waranecki, P., Geisemeyer, N., de Gooijer, M. C., Breur, M., Koster, J., Veldhuijzen van Zanten, S. E. M., Bugiani, M., Franke, N. E., Reddy, A., Wesseling, P., Kaspers, G. J. L. & Hulleman, E., 17 Sept 2024, In: Cell Reports Medicine. 5, 9, 101700.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
The heterogeneous sensitivity of pediatric brain tumors to different oncolytic viruses is predicted by unique gene expression profiles
Vazaios, K., Stavrakaki, Ε., Vogelezang, L. B., Ju, J., Waranecki, P., Metselaar, D. S., Meel, M. H., Kemp, V., van den Hoogen, B. G., Hoeben, R. C., Chiocca, E. A., Goins, W. F., Stubbs, A., Li, Y., Alonso, M. M., Calkoen, F. G., Hulleman, E., van der Lugt, J. & Lamfers, M. L. M., 20 Jun 2024, In: Molecular Therapy Oncology. 32, 2, 200804.Research output: Contribution to journal › Article › peer-review
Open Access6 Citations (Scopus) -
Microglia in pediatric brain tumors: The missing link to successful immunotherapy
du Chatinier, A., Velilla, I. Q., Meel, M. H., Hoving, E. W., Hulleman, E. & Metselaar, D. S., 21 Nov 2023, In: Cell Reports Medicine. 4, 11, 101246.Research output: Contribution to journal › Review article › peer-review
Open Access18 Citations (Scopus) -
AURKA and PLK1 inhibition selectively and synergistically block cell cycle progression in diffuse midline glioma
Metselaar, D. S., du Chatinier, A., Meel, M. H., ter Huizen, G., Waranecki, P., Goulding, J. R., Bugiani, M., Koster, J., Kaspers, G. J. L. & Hulleman, E., 17 Jun 2022, In: iScience. 25, 6, p. 104398 104398.Research output: Contribution to journal › Article › peer-review
Open Access20 Citations (Scopus) -
Clustered regularly interspaced short palindromic repeats screens in pediatric tumours: A review
van Mackelenbergh, M., Metselaar, D., Meel, M. H. & Hulleman, E., Dec 2022, In: Clinical and Translational Discovery. 2, 4, e2142.Research output: Contribution to journal › Review article › peer-review
Open Access