Henk Stunnenberg

Calculated based on number of publications stored in Pure and citations from Scopus
1978 …2023

Research activity per year

Search results

  • 2017

    p63 exerts spatio-temporal control of palatal epithelial cell fate to prevent cleft palate

    Richardson, R., Mitchell, K., Hammond, N. L., Mollo, M. R., Kouwenhoven, E. N., Wyatt, N. D., Donaldson, I. J., Zeef, L., Burgis, T., Blance, R., van Heeringen, S. J., Stunnenberg, H. G., Zhou, H., Missero, C., Romano, R. A., Sinha, S., Dixon, M. J. & Dixon, J., 2017, In: PLoS Genetics. 13, 6, e1006828.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    31 Citations (Scopus)
  • Platelet function is modified by common sequence variation in megakaryocyte super enhancers

    Petersen, R., Lambourne, J. J., Javierre, B. M., Grassi, L., Kreuzhuber, R., Ruklisa, D., Rosa, I. M., Tomé, A. R., Elding, H., Van Geffen, J. P., Jiang, T., Farrow, S., Cairns, J., Al-Subaie, A. M., Ashford, S., Attwood, A., Batista, J., Bouman, H., Burden, F., Choudry, F. A., & 39 othersClarke, L., Flicek, P., Garner, S. F., Haimel, M., Kempster, C., Ladopoulos, V., Lenaerts, A. S., Materek, P. M., McKinney, H., Meacham, S., Mead, D., Nagy, M., Penkett, C. J., Rendon, A., Seyres, D., Sun, B., Tuna, S., Van Der Weide, M. E., Wingett, S. W., Martens, J. H., Stegle, O., Richardson, S., Vallier, L., Roberts, D. J., Freson, K., Wernisch, L., Stunnenberg, H. G., Danesh, J., Fraser, P., Soranzo, N., Butterworth, A. S., Heemskerk, J. W., Turro, E., Spivakov, M., Ouwehand, W. H., Astle, W. J., Downes, K., Kostadima, M. & Frontini, M., 13 Jul 2017, In: Nature Communications. 8, 16058.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    41 Citations (Scopus)
  • Prc1 prevents replication stress during chondrogenic transit amplification

    Spaapen, F., Eijssen, L. M. T., Adriaens, M. E., Welting, T. J., Prickaerts, P., Salvaing, J., Dahlmans, V. E. H., Surtel, D. A. M., Kruitz, F., Kuijer, R., Takihara, Y., Marks, H., Stunnenberg, H. G., Wouters, B. G., Vidal, M. & Voncken, J. W., Dec 2017, In: Epigenomes. 1, 3, 22.

    Research output: Contribution to journalArticlepeer-review

    Open Access
  • Predicting stimulation-dependent enhancer-promoter interactions fromv ChIP-Seq time course data

    Dzida, T., Iqbal, M., Charapitsa, I., Reid, G., Stunnenberg, H., Matarese, F., Grote, K., Honkela, A. & Rattray, M., 2017, In: PeerJ. 2017, 9, e3742.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    8 Citations (Scopus)
  • Somatic mutations reveal asymmetric cellular dynamics in the early human embryo

    Ju, Y. S., Martincorena, I., Gerstung, M., Petljak, M., Alexandrov, L. B., Rahbari, R., Wedge, D. C., Davies, H. R., Ramakrishna, M., Fullam, A., Martin, S., Alder, C., Patel, N., Gamble, S., O'Meara, S., Giri, DI. D., Sauer, T., Pinder, S. E., Purdie, C. A., Borg, Å., & 21 othersStunnenberg, H., Van De Vijver, M., Tan, B. K. T., Caldas, C., Tutt, A., Ueno, N. T., Van 'T Veer, L. J., Martens, J. W. M., Sotiriou, C., Knappskog, S., Span, P. N., Lakhani, S. R., Eyfjörd, J. E., Børresen-Dale, A. L., Richardson, A., Thompson, A. M., Viari, A., Hurles, M. E., Nik-Zainal, S., Campbell, P. J. & Stratton, M. R., 30 Mar 2017, In: Nature. 543, 7647, p. 714-718 5 p.

    Research output: Contribution to journalArticlepeer-review

    178 Citations (Scopus)
  • The interplay of epigenetic marks during stem cell differentiation and development

    Atlasi, Y. & Stunnenberg, H. G., 1 Nov 2017, In: Nature Reviews Genetics. 18, 11, p. 643-658 16 p.

    Research output: Contribution to journalReview articlepeer-review

    319 Citations (Scopus)
  • The non-coding variant rs1800734 enhances DCLK3 expression through long-range interaction and promotes colorectal cancer progression

    Liu, N. Q., Ter Huurne, M., Nguyen, L. N., Peng, T., Wang, S. Y., Studd, J. B., Joshi, O., Ongen, H., Bramsen, J. B., Yan, J., Andersen, C. L., Taipale, J., Dermitzakis, E. T., Houlston, R. S., Hubner, N. C. & Stunnenberg, H. G., 14 Feb 2017, In: Nature Communications. 8, 14418.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    44 Citations (Scopus)
  • Time-resolved analysis of DNA-protein interactions in living cells by UV laser pulses

    Nebbioso, A., Benedetti, R., Conte, M., Carafa, V., De Bellis, F., Shaik, J., Matarese, F., Della Ventura, B., Gesuele, F., Velotta, R., Martens, J. H. A., Stunnenberg, H. G., Altucci, C. & Altucci, L., 1 Dec 2017, In: Scientific Reports. 7, 1, 11725.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    13 Citations (Scopus)
  • Tracking the embryonic stem cell transition from ground state pluripotency

    Kalkan, T., Olova, N., Roode, M., Mulas, C., Lee, H. J., Nett, I., Marks, H., Walker, R., Stunnenberg, H. G., Lilley, K. S., Nichols, J., Reik, W., Bertone, P. & Smith, A., 1 Apr 2017, In: Development. 144, 7, p. 1221-1234 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    183 Citations (Scopus)
  • Transcriptional and epigenetic control in mouse pluripotency: lessons from in vivo and in vitro studies

    Habibi, E. & Stunnenberg, H. G., Oct 2017, In: Current Opinion in Genetics and Development. 46, p. 114-122 9 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    12 Citations (Scopus)
  • Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway

    Crişan, T. O., Cleophas, M. C. P., Novakovic, B., Erler, K., Van De Veerdonk, F. L., Stunnenberg, H. G., Netea, M. G., Dinarello, C. A. & Joosten, L. A. B., 23 May 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 21, p. 5485-5490 6 p.

    Research output: Contribution to journalArticlepeer-review

    105 Citations (Scopus)
  • Vitamin C and L-Proline Antagonistic Effects Capture Alternative States in the Pluripotency Continuum

    D'Aniello, C., Habibi, E., Cermola, F., Paris, D., Russo, F., Fiorenzano, A., Di Napoli, G., Melck, D. J., Cobellis, G., Angelini, C., Fico, A., Blelloch, R., Motta, A., Stunnenberg, H. G., De Cesare, D., Patriarca, E. J. & Minchiotti, G., 10 Jan 2017, In: Stem Cell Reports. 8, 1, p. 1-10 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    36 Citations (Scopus)
  • 2016

    Breast cancer genome and transcriptome integration implicates specific mutational signatures with immune cell infiltration

    Smid, M., Rodríguez-González, F. G., Sieuwerts, A. M., Salgado, R., Prager-Van Der Smissen, W. J. C., Vlugt-Daane, M. V. D., Van Galen, A., Nik-Zainal, S., Staaf, J., Brinkman, A. B., Van De Vijver, M. J., Richardson, A. L., Fatima, A., Berentsen, K., Butler, A., Martin, S., Davies, H. R., Debets, R., Gelder, M. E. M. V., Van Deurzen, C. H. M., & 27 othersMacgrogan, G., Van Den Eynden, G. G. G. M., Purdie, C., Thompson, A. M., Caldas, C., Span, P. N., Simpson, P. T., Lakhani, S. R., Van Laere, S., Desmedt, C., Ringnér, M., Tommasi, S., Eyford, J., Broeks, A., Vincent-Salomon, A., Futreal, P. A., Knappskog, S., King, T., Thomas, G., Viari, A., Langerød, A., Børresen-Dale, A. L., Birney, E., Stunnenberg, H. G., Stratton, M., Foekens, J. A. & Martens, J. W. M., 26 Sept 2016, In: Nature Communications. 7, 12910.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    89 Citations (Scopus)
  • Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2

    Tahmasebi, S., Jafarnejad, S. M., Tam, I. S., Gonatopoulos-Pournatzis, T., Matta-Camacho, E., Tsukumo, Y., Yanagiya, A., Li, W., Atlasi, Y., Caron, M., Braunschweig, U., Pearl, D., Khoutorsky, A., Gkogkas, C. G., Nadon, R., Bourque, G., Yang, X. J., Tian, B., Stunnenberg, H. G., Yamanaka, Y., & 3 othersBlencowe, B. J., Giguère, V. & Sonenberg, N., 1 Nov 2016, In: Proceedings of the National Academy of Sciences of the United States of America. 113, 44, p. 12360-12367 8 p.

    Research output: Contribution to journalArticlepeer-review

    46 Citations (Scopus)
  • Decoding the DNA Methylome of Mantle Cell Lymphoma in the Light of the Entire B Cell Lineage

    Queirós, A. C., Beekman, R., Vilarrasa-Blasi, R., Duran-Ferrer, M., Clot, G., Merkel, A., Raineri, E., Russiñol, N., Castellano, G., Beà, S., Navarro, A., Kulis, M., Verdaguer-Dot, N., Jares, P., Enjuanes, A., Calasanz, M. J., Bergmann, A., Vater, I., Salaverría, I., van de Werken, H. J. G., & 15 othersWilson, W. H., Datta, A., Flicek, P., Royo, R., Martens, J., Giné, E., Lopez-Guillermo, A., Stunnenberg, H. G., Klapper, W., Pott, C., Heath, S., Gut, I. G., Siebert, R., Campo, E. & Martín-Subero, J. I., 14 Nov 2016, In: Cancer Cell. 30, 5, p. 806-821 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    95 Citations (Scopus)
  • Distinct Trends of DNA Methylation Patterning in the Innate and Adaptive Immune Systems

    Schuyler, R. P., Merkel, A., Raineri, E., Altucci, L., Vellenga, E., Martens, J. H. A., Pourfarzad, F., Kuijpers, T. W., Burden, F., Farrow, S., Downes, K., Ouwehand, W. H., Clarke, L., Datta, A., Lowy, E., Flicek, P., Frontini, M., Stunnenberg, H. G., Martín-Subero, J. I., Gut, I., & 1 othersHeath, S., 15 Nov 2016, In: Cell Reports. 17, 8, p. 2101-2111 11 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    49 Citations (Scopus)
  • DNA Methylation Dynamics of Human Hematopoietic Stem Cell Differentiation

    Farlik, M., Halbritter, F., Müller, F., Choudry, F. A., Ebert, P., Klughammer, J., Farrow, S., Santoro, A., Ciaurro, V., Mathur, A., Uppal, R., Stunnenberg, H. G., Ouwehand, W. H., Laurenti, E., Lengauer, T., Frontini, M. & Bock, C., 1 Dec 2016, In: Cell Stem Cell. 19, 6, p. 808-822 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    177 Citations (Scopus)
  • Dynamic chromatin organization: Role in development and disease

    Kuznetsova, T. & Stunnenberg, H. G., 1 Jul 2016, In: International Journal of Biochemistry and Cell Biology. 76, p. 119-122 4 p.

    Research output: Contribution to journalShort surveypeer-review

    3 Citations (Scopus)
  • eFORGE: A Tool for Identifying Cell Type-Specific Signal in Epigenomic Data

    Breeze, C. E., Paul, D. S., van Dongen, J., Butcher, L. M., Ambrose, J. C., Barrett, J. E., Lowe, R., Rakyan, V. K., Iotchkova, V., Frontini, M., Downes, K., Ouwehand, W. H., Laperle, J., Jacques, P. É., Bourque, G., Bergmann, A. K., Siebert, R., Vellenga, E., Saeed, S., Matarese, F., & 7 othersMartens, J. H. A., Stunnenberg, H. G., Teschendorff, A. E., Herrero, J., Birney, E., Dunham, I. & Beck, S., 15 Nov 2016, In: Cell Reports. 17, 8, p. 2137-2150 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    82 Citations (Scopus)
  • Environment-induced epigenetic reprogramming in genomic regulatory elements in smoking mothers and their children

    Bauer, T., Trump, S., Ishaque, N., Thürmann, L., Gu, L., Bauer, M., Bieg, M., Gu, Z., Weichenhan, D., Mallm, J. P., Röder, S., Herberth, G., Takada, E., Mücke, O., Winter, M., Junge, K. M., Grützmann, K., Rolle-Kampczyk, U., Wang, Q., Lawerenz, C., & 13 othersBorte, M., Polte, T., Schlesner, M., Schanne, M., Wiemann, S., Geörg, C., Stunnenberg, H. G., Plass, C., Rippe, K., Mizuguchi, J., Herrmann, C., Eils, R. & Lehmann, I., 1 Mar 2016, In: Molecular Systems Biology. 12, 3, 861.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    86 Citations (Scopus)
  • Epigenetic memory: A macrophage perspective

    Logie, C. & Stunnenberg, H. G., 1 Aug 2016, In: Seminars in Immunology. 28, 4, p. 359-367 9 p.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    28 Citations (Scopus)
  • Erratum: The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery (Cell (2016) 167(5) (1145–1149) (S0092867416315288) (10.1016/j.cell.2016.11.007))

    The International Human Epigenome Consortium, 15 Dec 2016, In: Cell. 167, 7, p. 1897 1 p.

    Research output: Contribution to journalComment/debate

    47 Citations (Scopus)
  • Erratum to: Dynamics of gene silencing during X inactivation using allele-specific RNA-seq [Genome Biol. 2015;16:149]

    Marks, H., Kerstens, H. H. D., Barakat, T. S., Splinter, E., Dirks, R. A. M., van Mierlo, G., Joshi, O., Wang, S. Y., Babak, T., Albers, C. A., Kalkan, T., Smith, A., Jouneau, A., de Laat, W., Gribnau, J. & Stunnenberg, H. G., 5 Feb 2016, In: Genome Biology. 17, 1, 22.

    Research output: Contribution to journalComment/debate

    Open Access
    1 Citation (Scopus)
  • GATA3-dependent cellular reprogramming requires activation-domain dependent recruitment of a chromatin remodeler

    Takaku, M., Grimm, S. A., Shimbo, T., Perera, L., Menafra, R., Stunnenberg, H. G., Archer, T. K., Machida, S., Kurumizaka, H. & Wade, P. A., 27 Feb 2016, In: Genome Biology. 17, 1, 36.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    99 Citations (Scopus)
  • Genetic Drivers of Epigenetic and Transcriptional Variation in Human Immune Cells

    Chen, L., Ge, B., Casale, F. P., Vasquez, L., Kwan, T., Garrido-Martín, D., Watt, S., Yan, Y., Kundu, K., Ecker, S., Datta, A., Richardson, D., Burden, F., Mead, D., Mann, A. L., Fernandez, J. M., Rowlston, S., Wilder, S. P., Farrow, S., Shao, X., & 56 othersLambourne, J. J., Redensek, A., Albers, C. A., Amstislavskiy, V., Ashford, S., Berentsen, K., Bomba, L., Bourque, G., Bujold, D., Busche, S., Caron, M., Chen, S. H., Cheung, W., Delaneau, O., Dermitzakis, E. T., Elding, H., Colgiu, I., Bagger, F. O., Flicek, P., Habibi, E., Iotchkova, V., Janssen-Megens, E., Kim, B., Lehrach, H., Lowy, E., Mandoli, A., Matarese, F., Maurano, M. T., Morris, J. A., Pancaldi, V., Pourfarzad, F., Rehnstrom, K., Rendon, A., Risch, T., Sharifi, N., Simon, M. M., Sultan, M., Valencia, A., Walter, K., Wang, S. Y., Frontini, M., Antonarakis, S. E., Clarke, L., Yaspo, M. L., Beck, S., Guigo, R., Rico, D., Martens, J. H. A., Ouwehand, W. H., Kuijpers, T. W., Paul, D. S., Stunnenberg, H. G., Stegle, O., Downes, K., Pastinen, T. & Soranzo, N., 17 Nov 2016, In: Cell. 167, 5, p. 1398-1414.e24

    Research output: Contribution to journalArticlepeer-review

    Open Access
    400 Citations (Scopus)
  • Genome-wide epigenomic profiling for biomarker discovery

    Dirks, R. A. M., Stunnenberg, H. G. & Marks, H., 21 Nov 2016, In: Clinical Epigenetics. 8, 1, 122.

    Research output: Contribution to journalReview articlepeer-review

    Open Access
    61 Citations (Scopus)
  • Glutaminolysis and Fumarate Accumulation Integrate Immunometabolic and Epigenetic Programs in Trained Immunity

    Arts, R. J. W., Novakovic, B., ter Horst, R., Carvalho, A., Bekkering, S., Lachmandas, E., Rodrigues, F., Silvestre, R., Cheng, S. C., Wang, S. Y., Habibi, E., Gonçalves, L. G., Mesquita, I., Cunha, C., van Laarhoven, A., van de Veerdonk, F. L., Williams, D. L., van der Meer, J. W. M., Logie, C., O'Neill, L. A., & 9 othersDinarello, C. A., Riksen, N. P., van Crevel, R., Clish, C., Notebaart, R. A., Joosten, L. A. B., Stunnenberg, H. G., Xavier, R. J. & Netea, M. G., 13 Dec 2016, In: Cell Metabolism. 24, 6, p. 807-819 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    535 Citations (Scopus)
  • Histone Methylation by the Kleefstra Syndrome Protein EHMT1 Mediates Homeostatic Synaptic Scaling

    Benevento, M., Iacono, G., Selten, M., Ba, W., Oudakker, A., Frega, M., Keller, J., Mancini, R., Lewerissa, E., Kleefstra, T., Stunnenberg, H. G., Zhou, H., van Bokhoven, H. & Nadif Kasri, N., 20 Jul 2016, In: Neuron. 91, 2, p. 341-355 15 p.

    Research output: Contribution to journalArticlepeer-review

    56 Citations (Scopus)
  • Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells

    von Meyenn, F., Iurlaro, M., Habibi, E., Liu, N. Q., Salehzadeh-Yazdi, A., Santos, F., Petrini, E., Milagre, I., Yu, M., Xie, Z., Kroeze, L. I., Nesterova, T. B., Jansen, J. H., Xie, H., He, C., Reik, W. & Stunnenberg, H. G., 16 Jun 2016, In: Molecular Cell. 62, 6, p. 848-861 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    141 Citations (Scopus)
  • Impairment of DNA Methylation Maintenance Is the Main Cause of Global Demethylation in Naive Embryonic Stem Cells [Molecular Cell 62, (2016) 848-861]

    von Meyenn, F., Iurlaro, M., Habibi, E., Liu, N. Q., Salehzadeh-Yazdi, A., Santos, F., Petrini, E., Milagre, I., Yu, M., Xie, Z., Kroeze, L. I., Nesterova, T. B., Jansen, J. H., Xie, H., He, C., Reik, W. & Stunnenberg, H. G., 16 Jun 2016, In: Molecular Cell. 62, 6, p. 983 1 p.

    Research output: Contribution to journalComment/debate

    Open Access
    35 Citations (Scopus)
  • Information recovery from low coverage whole-genome bisulfite sequencing

    Libertini, E., Heath, S. C., Hamoudi, R. A., Gut, M., Ziller, M. J., Czyz, A., Ruotti, V., Stunnenberg, H. G., Frontini, M., Ouwehand, W. H., Meissner, A., Gut, I. G. & Beck, S., 27 Jun 2016, In: Nature Communications. 7, 11306.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    30 Citations (Scopus)
  • Landscape of somatic mutations in 560 breast cancer whole-genome sequences

    Nik-Zainal, S., Davies, H., Staaf, J., Ramakrishna, M., Glodzik, D., Zou, X., Martincorena, I., Alexandrov, L. B., Martin, S., Wedge, D. C., Van Loo, P., Ju, Y. S., Smid, M., Brinkman, A. B., Morganella, S., Aure, M. R., Lingjærde, O. C., Langerød, A., Ringnér, M., Ahn, S. M., & 68 othersBoyault, S., Brock, J. E., Broeks, A., Butler, A., Desmedt, C., Dirix, L., Dronov, S., Fatima, A., Foekens, J. A., Gerstung, M., Hooijer, G. K. J., Jang, S. J., Jones, D. R., Kim, H. Y., King, T. A., Krishnamurthy, S., Lee, H. J., Lee, J. Y., Li, Y., McLaren, S., Menzies, A., Mustonen, V., O'Meara, S., Pauporté, I., Pivot, X., Purdie, C. A., Raine, K., Ramakrishnan, K., Rodríguez-González, F. G., Romieu, G., Sieuwerts, A. M., Simpson, P. T., Shepherd, R., Stebbings, L., Stefansson, O. A., Teague, J., Tommasi, S., Treilleux, I., Van Den Eynden, G. G., Vermeulen, P., Vincent-Salomon, A., Yates, L., Caldas, C., Veer, L. V. T., Tutt, A., Knappskog, S., Tan, B. K. T., Jonkers, J., Borg, Å., Ueno, N. T., Sotiriou, C., Viari, A., Futreal, P. A., Campbell, P. J., Span, P. N., Van Laere, S., Lakhani, S. R., Eyfjord, J. E., Thompson, A. M., Birney, E., Stunnenberg, H. G., Van De Vijver, M. J., Martens, J. W. M., Børresen-Dale, A. L., Richardson, A. L., Kong, G., Thomas, G. & Stratton, M. R., 2 May 2016, In: Nature. 534, 7605, p. 47-54 8 p.

    Research output: Contribution to journalArticlepeer-review

    1477 Citations (Scopus)
  • Lineage-Specific Genome Architecture Links Enhancers and Non-coding Disease Variants to Target Gene Promoters

    Javierre, B. M., Sewitz, S., Cairns, J., Wingett, S. W., Várnai, C., Thiecke, M. J., Freire-Pritchett, P., Spivakov, M., Fraser, P., Burren, O. S., Cutler, A. J., Todd, J. A., Wallace, C., Wilder, S. P., Kreuzhuber, R., Kostadima, M., Zerbino, D. R., Stegle, O., Burden, F., Farrow, S., & 19 othersRehnström, K., Downes, K., Grassi, L., Ouwehand, W. H., Frontini, M., Hill, S. M., Wang, F., Stunnenberg, H. G., Martens, J. H., Kim, B., Sharifi, N., Janssen-Megens, E. M., Yaspo, M. L., Linser, M., Kovacsovics, A., Clarke, L., Richardson, D., Datta, A. & Flicek, P., 17 Nov 2016, In: Cell. 167, 5, p. 1369-1384.e19

    Research output: Contribution to journalArticlepeer-review

    Open Access
    617 Citations (Scopus)
  • MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML

    Vegi, N. M., Klappacher, J., Oswald, F., Mulaw, M. A., Mandoli, A., Thiel, V. N., Bamezai, S., Feder, K., Martens, J. H. A., Rawat, V. P. S., Mandal, T., Quintanilla-Martinez, L., Spiekermann, K., Hiddemann, W., Döhner, K., Döhner, H., Stunnenberg, H. G., Feuring-Buske, M. & Buske, C., 12 Jul 2016, In: Cell Reports. 16, 2, p. 498-507 10 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    32 Citations (Scopus)
  • Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis

    van den Boom, V., Maat, H., Geugien, M., Rodríguez López, A., Sotoca, A. M., Jaques, J., Brouwers-Vos, A. Z., Fusetti, F., Groen, R. W. J., Yuan, H., Martens, A. C. M., Stunnenberg, H. G., Vellenga, E., Martens, J. H. A. & Schuringa, J. J., 12 Jan 2016, In: Cell Reports. 14, 2, p. 332-346 15 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    108 Citations (Scopus)
  • Recruitment of the mammalian histone-modifying EMSY complex to target genes is regulated by ZNF131

    Varier, R. A., De Santa Pau, E. C., Van Der Groep, P., Lindeboom, R. G. H., Matarese, F., Mensinga, A., Smits, A. H., Edupuganti, R. R., Baltissen, M. P., Jansen, P. W. T. C., Hoeve, N. T., Van Weely, D. R., Poser, I., Van Diest, P. J., Stunnenberg, H. G. & Vermeulen, M., 1 Apr 2016, In: Journal of Biological Chemistry. 291, 14, p. 7313-7324 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    30 Citations (Scopus)
  • Saturation analysis for whole-genome bisulfite sequencing data

    Libertini, E., Heath, S. C., Hamoudi, R. A., Gut, M., Ziller, M. J., Herrero, J., Czyz, A., Ruotti, V., Stunnenberg, H. G., Frontini, M., Ouwehand, W. H., Meissner, A., Gut, I. G. & Beck, S., 2016, In: Nature Biotechnology. 34, 7, p. 691-693 3 p.

    Research output: Contribution to journalLetterpeer-review

    26 Citations (Scopus)
  • The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease

    Astle, W. J., Elding, H., Jiang, T., Allen, D., Ruklisa, D., Mann, A. L., Mead, D., Bouman, H., Riveros-Mckay, F., Kostadima, M. A., Lambourne, J. J., Sivapalaratnam, S., Downes, K., Kundu, K., Bomba, L., Berentsen, K., Bradley, J. R., Daugherty, L. C., Delaneau, O., Freson, K., & 54 othersGarner, S. F., Grassi, L., Guerrero, J., Haimel, M., Janssen-Megens, E. M., Kaan, A., Kamat, M., Kim, B., Mandoli, A., Marchini, J., Martens, J. H. A., Meacham, S., Megy, K., O'Connell, J., Petersen, R., Sharifi, N., Sheard, S. M., Staley, J. R., Tuna, S., van der Ent, M., Walter, K., Wang, S. Y., Wheeler, E., Wilder, S. P., Iotchkova, V., Moore, C., Sambrook, J., Stunnenberg, H. G., Di Angelantonio, E., Kaptoge, S., Kuijpers, T. W., Carrillo-de-Santa-Pau, E., Juan, D., Rico, D., Valencia, A., Chen, L., Ge, B., Vasquez, L., Kwan, T., Garrido-Martín, D., Watt, S., Yang, Y., Guigo, R., Beck, S., Paul, D. S., Pastinen, T., Bujold, D., Bourque, G., Frontini, M., Danesh, J., Roberts, D. J., Ouwehand, W. H., Butterworth, A. S. & Soranzo, N., 17 Nov 2016, In: Cell. 167, 5, p. 1415-1429.e19

    Research output: Contribution to journalArticlepeer-review

    Open Access
    736 Citations (Scopus)
  • The Hematopoietic Transcription Factors RUNX1 and ERG Prevent AML1-ETO Oncogene Overexpression and Onset of the Apoptosis Program in t(8;21) AMLs

    Mandoli, A., Singh, A. A., Prange, K. H. M., Tijchon, E., Oerlemans, M., Dirks, R., Ter Huurne, M., Wierenga, A. T. J., Janssen-Megens, E. M., Berentsen, K., Sharifi, N., Kim, B., Matarese, F., Nguyen, L. N., Hubner, N. C., Rao, N. A., van den Akker, E., Altucci, L., Vellenga, E., Stunnenberg, H. G., & 1 othersMartens, J. H. A., 15 Nov 2016, In: Cell Reports. 17, 8, p. 2087-2100 14 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    45 Citations (Scopus)
  • The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

    Stunnenberg, H. G., Abrignani, S., Adams, D., de Almeida, M., Altucci, L., Amin, V., Amit, I., Antonarakis, S. E., Aparicio, S., Arima, T., Arrigoni, L., Arts, R., Asnafi, V., Badosa, M. E., Bae, J. B., Bassler, K., Beck, S., Berkman, B., Bernstein, B. E., Bilenky, M., & 210 othersBird, A., Bock, C., Boehm, B., Bourque, G., Breeze, C. E., Brors, B., Bujold, D., Burren, O., Bussemakers, M. J., Butterworth, A., Campo, E., Carrillo-de-Santa-Pau, E., Chadwick, L., Chan, K. M., Chen, W., Cheung, T. H., Chiapperino, L., Choi, N. H., Chung, H. R., Clarke, L., Connors, J. M., Cronet, P., Danesh, J., Dermitzakis, M., Drewes, G., Durek, P., Dyke, S., Dylag, T., Eaves, C. J., Ebert, P., Eils, R., Eils, J., Ennis, C. A., Enver, T., Feingold, E. A., Felder, B., Ferguson-Smith, A., Fitzgibbon, J., Flicek, P., Foo, R. S. Y., Fraser, P., Frontini, M., Furlong, E., Gakkhar, S., Gasparoni, N., Gasparoni, G., Geschwind, D. H., Glažar, P., Graf, T., Grosveld, F., Guan, X. Y., Guigo, R., Gut, I. G., Hamann, A., Han, B. G., Harris, R. A., Heath, S., Helin, K., Hengstler, J. G., Heravi-Moussavi, A., Herrup, K., Hill, S., Hilton, J. A., Hitz, B. C., Horsthemke, B., Hu, M., Hwang, J. Y., Ip, N. Y., Ito, T., Javierre, B. M., Jenko, S., Jenuwein, T., Joly, Y., Jones, S. J. M., Kanai, Y., Kang, H. G., Karsan, A., Kiemer, A. K., Kim, S. C., Kim, B. J., Kim, H. H., Kimura, H., Kinkley, S., Klironomos, F., Koh, I. U., Kostadima, M., Kressler, C., Kreuzhuber, R., Kundaje, A., Küppers, R., Larabell, C., Lasko, P., Lathrop, M., Lee, D. H. S., Lee, S., Lehrach, H., Leitão, E., Lengauer, T., Lernmark, Å., Leslie, R. D., Leung, G. K. K., Leung, D., Loeffler, M., Ma, Y., Mai, A., Manke, T., Marcotte, E. R., Marra, M. A., Martens, J. H. A., Martin-Subero, J. I., Maschke, K., Merten, C., Milosavljevic, A., Minucci, S., Mitsuyama, T., Moore, R. A., Müller, F., Mungall, A. J., Netea, M. G., Nordström, K., Norstedt, I., Okae, H., Onuchic, V., Ouellette, F., Ouwehand, W., Pagani, M., Pancaldi, V., Pap, T., Pastinen, T., Patel, R., Paul, D. S., Pazin, M. J., Pelicci, P. G., Phillips, A. G., Polansky, J., Porse, B., Pospisilik, J. A., Prabhakar, S., Procaccini, D. C., Radbruch, A., Rajewsky, N., Rakyan, V., Reik, W., Ren, B., Richardson, D., Richter, A., Rico, D., Roberts, D. J., Rosenstiel, P., Rothstein, M., Salhab, A., Sasaki, H., Satterlee, J. S., Sauer, S., Schacht, C., Schmidt, F., Schmitz, G., Schreiber, S., Schröder, C., Schübeler, D., Schultze, J. L., Schulyer, R. P., Schulz, M., Seifert, M., Shirahige, K., Siebert, R., Sierocinski, T., Siminoff, L., Sinha, A., Soranzo, N., Spicuglia, S., Spivakov, M., Steidl, C., Strattan, J. S., Stratton, M., Südbeck, P., Sun, H., Suzuki, N., Suzuki, Y., Tanay, A., Torrents, D., Tyson, F. L., Ulas, T., Ullrich, S., Ushijima, T., Valencia, A., Vellenga, E., Vingron, M., Wallace, C., Wallner, S., Walter, J., Wang, H., Weber, S., Weiler, N., Weller, A., Weng, A., Wilder, S., Wiseman, S. M., Wu, A. R., Wu, Z., Xiong, J., Yamashita, Y., Yang, X., Yap, D. Y., Yip, K. Y., Yip, S., Yoo, J. I., Zerbino, D., Zipprich, G. & Hirst, M., 17 Nov 2016, In: Cell. 167, 5, p. 1145-1149 5 p.

    Research output: Contribution to journalComment/debate

    285 Citations (Scopus)
  • The oncofusion protein FUS-ERG targets key hematopoietic regulators and modulates the all-trans retinoic acid signaling pathway in t(16;21) acute myeloid leukemia

    Sotoca, A. M., Prange, K. H. M., Reijnders, B., Mandoli, A., Nguyen, L. N., Stunnenberg, H. G. & Martens, J. H. A., 14 Apr 2016, In: Oncogene. 35, 15, p. 1965-1976 12 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    34 Citations (Scopus)
  • The topography of mutational processes in breast cancer genomes

    Morganella, S., Alexandrov, L. B., Glodzik, D., Zou, X., Davies, H., Staaf, J., Sieuwerts, A. M., Brinkman, A. B., Martin, S., Ramakrishna, M., Butler, A., Kim, H. Y., Borg, Å., Sotiriou, C., Futreal, P. A., Campbell, P. J., Span, P. N., Van Laere, S., Lakhani, S. R., Eyfjord, J. E., & 13 othersThompson, A. M., Stunnenberg, H. G., Van De Vijver, M. J., Martens, J. W. M., Børresen-Dale, A. L., Richardson, A. L., Kong, G., Thomas, G., Sale, J., Rada, C., Stratton, M. R., Birney, E. & Nik-Zainal, S., 2 May 2016, In: Nature Communications. 7, 11383.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    193 Citations (Scopus)
  • Trained immunity: A program of innate immune memory in health and disease

    Netea, M. G., Joosten, L. A. B., Latz, E., Mills, K. H. G., Natoli, G., Stunnenberg, H. G., O'Neill, L. A. J. & Xavier, R. J., 22 Apr 2016, In: Science. 352, 6284, p. 427 1 p.

    Research output: Contribution to journalReview articlepeer-review

    1613 Citations (Scopus)
  • Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells

    De Simone, M., Arrigoni, A., Rossetti, G., Gruarin, P., Ranzani, V., Politano, C., Bonnal, R. J. P., Provasi, E., Sarnicola, M. L., Panzeri, I., Moro, M., Crosti, M., Mazzara, S., Vaira, V., Bosari, S., Palleschi, A., Santambrogio, L., Bovo, G., Zucchini, N., Totis, M., & 11 othersGianotti, L., Cesana, G., Perego, R. A., Maroni, N., Pisani Ceretti, A., Opocher, E., De Francesco, R., Geginat, J., Stunnenberg, H. G., Abrignani, S. & Pagani, M., 15 Nov 2016, In: Immunity. 45, 5, p. 1135-1147 13 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    450 Citations (Scopus)
  • ZMYND8 Co-localizes with NuRD on Target Genes and Regulates Poly(ADP-Ribose)-Dependent Recruitment of GATAD2A/NuRD to Sites of DNA Damage

    Spruijt, C. G., Luijsterburg, M. S., Menafra, R., Lindeboom, R. G. H., Jansen, P. W. T. C., Edupuganti, R. R., Baltissen, M. P., Wiegant, W. W., Voelker-Albert, M. C., Matarese, F., Mensinga, A., Poser, I., Vos, H. R., Stunnenberg, H. G., van Attikum, H. & Vermeulen, M., 11 Oct 2016, In: Cell Reports. 17, 3, p. 783-798 16 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    80 Citations (Scopus)
  • β-Glucan Reverses the Epigenetic State of LPS-Induced Immunological Tolerance

    Novakovic, B., Habibi, E., Wang, S. Y., Arts, R. J. W., Davar, R., Megchelenbrink, W., Kim, B., Kuznetsova, T., Kox, M., Zwaag, J., Matarese, F., van Heeringen, S. J., Janssen-Megens, E. M., Sharifi, N., Wang, C., Keramati, F., Schoonenberg, V., Flicek, P., Clarke, L., Pickkers, P., & 6 othersHeath, S., Gut, I., Netea, M. G., Martens, J. H. A., Logie, C. & Stunnenberg, H. G., 17 Nov 2016, In: Cell. 167, 5, p. 1354-1368.e14

    Research output: Contribution to journalArticlepeer-review

    Open Access
    394 Citations (Scopus)
  • 2015

    A Me6Age for pluripotency

    Stunnenberg, H. G., Vermeulen, M. & Atlasi, Y., 6 Feb 2015, In: Science. 347, 6222, p. 614-615 2 p.

    Research output: Contribution to journalReview articlepeer-review

    6 Citations (Scopus)
  • A quantitative proteomics tool to identify DNA-protein interactions in primary cells or blood

    Hubner, N. C., Nguyen, L. N., Hornig, N. C. & Stunnenberg, H. G., 6 Feb 2015, In: Journal of Proteome Research. 14, 2, p. 1315-1329 15 p.

    Research output: Contribution to journalArticlepeer-review

    28 Citations (Scopus)
  • Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration

    Dubos, A., Castells-Nobau, A., Meziane, H., Oortveld, M. A. W., Houbaert, X., Iacono, G., Martin, C., Mittelhaeuser, C., Lalanne, V., Kramer, J. M., Bhukel, A., Quentin, C., Slabbert, J., Verstreken, P., Sigrist, S. J., Messaddeq, N., Birling, M. C., Selloum, M., Stunnenberg, H. G., Humeau, Y., & 2 othersSchenck, A. & Herault, Y., 1 Dec 2015, In: Human Molecular Genetics. 24, 23, p. 6736-6755 20 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    49 Citations (Scopus)
  • DNA Methylation of the Aryl Hydrocarbon Receptor Repressor Associations with Cigarette Smoking and Subclinical Atherosclerosis

    Reynolds, L. M., Wan, M., Ding, J., Taylor, J. R., Lohman, K., Su, D., Bennett, B. D., Porter, D. K., Gimple, R., Pittman, G. S., Wang, X., Howard, T. D., Siscovick, D., Psaty, B. M., Shea, S., Burke, G. L., Jacobs, D. R., Rich, S. S., Hixson, J. E., Stein, J. H., & 8 othersStunnenberg, H., Barr, R. G., Kaufman, J. D., Post, W. S., Hoeschele, I., Herrington, D. M., Bell, D. A. & Liu, Y., 1 Oct 2015, In: Circulation: Cardiovascular Genetics. 8, 5, p. 707-716 10 p.

    Research output: Contribution to journalArticlepeer-review

    98 Citations (Scopus)