Research output per year
Research output per year
Personal profile
Research interests
The Drost group is studying in the molecular mechanisms underpinning the development of childhood solid tumors, with a primary focus on renal tumors, rhabdoid tumors, and soft tissue sarcomas. We take a multidisciplinary approach by using unique model systems, such as organoid technology, in combination with multi-omics and lineage tracing technologies to increase our understanding of the origin of these tumors and to develop new therapeutic strategies.
Research interests
Onderzoeksbelangen
Education/Academic qualification
PhD, Netherlands Cancer Institute
Award Date: 28 Mar 2012
Master, Vrije Universiteit Amsterdam
Award Date: 31 Aug 2005
Bachelor, Institute of Life Sciences and Chemistry at Hogeschool Utrecht
Award Date: 31 Aug 2003
External positions
Junior Principal Investigator, Oncode Institute
1 Jan 2019 → …
Keywords
- Q Science (General)
- QH301 Biology
- QH426 Genetics
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Atypical teratoid/rhabdoid tumoroids reveal subgroup-specific drug vulnerabilities
Paassen, I., Williams, J., Ríos Arceo, C., Ringnalda, F., Mercer, K. S., Buhl, J. L., Moreno, N., Federico, A., Franke, N. E., Kranendonk, M., Upadhyaya, S. A., Kerl, K., van de Wetering, M., Clevers, H., Kool, M., Hoving, E. W., Roussel, M. F. & Drost, J., May 2023, In: Oncogene. 42, 20, p. 1661-1671 11 p.Research output: Contribution to journal › Article › peer-review
Open Access -
ErbB2 (HER2)-CAR-NK-92 cells for enhanced immunotherapy of metastatic fusion-driven alveolar rhabdomyosarcoma
Heim, C., Moser, L. M., Kreyenberg, H., Bonig, H. B., Tonn, T., Wels, W. S., Gradhand, E., Ullrich, E., Meister, M. T., Koerkamp, M. G., Holstege, F. C. P., Drost, J., Klusmann, J-H., Bader, P., Merker, M. & Rettinger, E., 2023, In: Frontiers in immunology. 14, p. 1228894Research output: Contribution to journal › Article › peer-review
Open Access -
Oncogenic signaling is coupled to colorectal cancer cell differentiation state
Sell, T., Klotz, C., Fischer, M. M., Astaburuaga-García, R., Krug, S., Drost, J., Clevers, H., Sers, C., Morkel, M. & Blüthgen, N., 5 Jun 2023, In: The Journal of Cell Biology. 222, 6Research output: Contribution to journal › Article › peer-review
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Systematic discovery of gene fusions in pediatric cancer by integrating RNA-seq and WGS
van Belzen, I. A. E. M., Cai, C., van Tuil, M., Badloe, S., Strengman, E., Janse, A., Verwiel, E. T. P., van der Leest, D. F. M., Kester, L., Molenaar, J. J., Meijerink, J., Drost, J., Peng, W. C., Kerstens, H. H. D., Tops, B. B. J., Holstege, F. C. P., Kemmeren, P. & Hehir-Kwa, J. Y., 3 Jul 2023, In: BMC Cancer. 23, 1, p. 618Research output: Contribution to journal › Article › peer-review
Open Access -
Characteristics and outcome of children with renal tumors in the Netherlands: The first five-year's experience of national centralization
Roy, P., van Peer, S. E., de Witte, M. M., Tytgat, G. A. M., Karim-Kos, H. E., van Grotel, M., van de Ven, C. P., Mavinkurve-Groothuis, A. M. C., Merks, J. H. M., Kuiper, R. P., Hol, J. A., Janssens, G. O. R., de Krijger, R. R., Jongmans, M. C. J., Drost, J., van der Steeg, A. F. W., Littooij, A. S., Wijnen, M. H. W. A., van Tinteren, H. & van den Heuvel-Eibrink, M. M., Jan 2022, In: PloS one. 17, 1 January, p. e0261729 e0261729.Research output: Contribution to journal › Article › peer-review
Open Access10 Citations (Scopus)
Prizes
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European Research Council (ERC) Starting Grant
Drost, Jarno (Recipient), 2019
Prize: Other distinction
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ITCC (Innovative Therapies for Children with Cancer in Europe) (External organisation)
Jarno Drost (Chair)
2021Activity: Membership › Membership of network
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Société Internationale d'Oncologie Pédiatrique Europe (SIOPE) (External organisation)
Jarno Drost (Chair)
2019Activity: Membership › Membership of network
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Société Internationale d'Oncologie Pédiatrique (SIOP) (External organisation)
Jarno Drost (Chair)
2019Activity: Membership › Membership of network
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ITCC (Innovative Therapies for Children with Cancer in Europe) (External organisation)
Jarno Drost (Chair)
2018 → 2021Activity: Membership › Membership of network