Research output per year
Research output per year
Personal profile
Research interests
The Drost group is studying in the molecular mechanisms underpinning the development of childhood solid tumors, with a primary focus on renal tumors, rhabdoid tumors, and soft tissue sarcomas. We take a multidisciplinary approach by using unique model systems, such as organoid technology, in combination with multi-omics and lineage tracing technologies to increase our understanding of the origin of these tumors and to develop new therapeutic strategies.
Research interests
Onderzoeksbelangen
Education/Academic qualification
PhD, Netherlands Cancer Institute
Award Date: 28 Mar 2012
Master, Vrije Universiteit Amsterdam
Award Date: 31 Aug 2005
Bachelor, Institute of Life Sciences and Chemistry at Hogeschool Utrecht
Award Date: 31 Aug 2003
External positions
Principal Investigator, Oncode Institute
1 Jan 2019 → …
Keywords
- Q Science (General)
- QH301 Biology
- QH426 Genetics
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Lactate controls cancer stemness and plasticity through epigenetic regulation
Nguyen, N. T. B., Gevers, S., Kok, R. N. U., Burgering, L. M., Neikes, H., Akkerman, N., Betjes, M. A., Ludikhuize, M. C., Gulersonmez, C., Stigter, E. C. A., Vercoulen, Y., Drost, J., Clevers, H., Vermeulen, M., van Zon, J. S., Tans, S. J., Burgering, B. M. T. & Rodríguez Colman, M. J., 1 Apr 2025, In: Cell Metabolism. 37, 4, p. 903-919.e10Research output: Contribution to journal › Article › peer-review
Open Access -
Predisposition Footprints in the Somatic Genome of Wilms Tumors
Treger, T. D., Wegert, J., Wenger, A., Coorens, T. H. H., Al-Saadi, R., Kemps, P. G., Kennedy, J., Parks, C., Anderson, N. D., Hodder, A., Letunovska, A., Jung, H., Ogbonnah, T., Trinh, M. K., Lee-Six, H., Morcrette, G., van den Heuvel-Eibrink, M. M., Drost, J., van Boxtel, R. & Bertrums, E. J. M. & 15 others, , 7 Feb 2025, In: Cancer discovery. 15, 2, p. 286-298 13 p.Research output: Contribution to journal › Article › peer-review
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Bevacizumab-containing treatment for relapsed or refractory Wilms tumor
Al-Jilaihawi, S., Spreafico, F., Mavinkurve-Groothuis, A., Drost, J., Perotti, D., Koenig, C. & Brok, J., Sept 2024, In: Expert review of anticancer therapy. 24, 9, p. 837-843 7 p.Research output: Contribution to journal › Article › peer-review
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Bridging the gap: advancing cancer cell culture to reveal key metabolic targets
Kes, M. M. G., Berkers, C. R. & Drost, J., 2024, In: Frontiers in Oncology. 14, p. 1480613Research output: Contribution to journal › Article › peer-review
Open Access -
Complex structural variation is prevalent and highly pathogenic in pediatric solid tumors
van Belzen, I. A. E. M., van Tuil, M., Badloe, S., Janse, A., Verwiel, E. T. P., Santoso, M., de Vos, S., Baker-Hernandez, J., Kerstens, H. H. D., Solleveld-Westerink, N., Meister, M. T., Drost, J., van den Heuvel-Eibrink, M. M., Merks, J. H. M., Molenaar, J. J., Peng, W. C., Tops, B. B. J., Holstege, F. C. P., Kemmeren, P. & Hehir-Kwa, J. Y., 13 Nov 2024, In: Cell genomics. 4, 11, p. 100675Research output: Contribution to journal › Article › peer-review
Open Access
Prizes
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Achieved tenure at Princess Máxima Center for Pediatric Oncology
Drost, J. (Recipient), 2021
Prize: Other distinction
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Cancer Research Horizons CYP Therapeutic Catalyst grant
Drost, J. (Recipient), 2024
Prize: Other distinction
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Paris Kids Cancer center (External organisation)
Drost, J. (Member)
2024 → …Activity: Membership › Membership of council
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Oncode Accelerator (External organisation)
Drost, J. (Member)
2023 → …Activity: Membership › Membership of council
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Oncode Accelerator (External organisation)
Drost, J. (Member)
2023Activity: Membership › Membership of board
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The Wilms Cancer Foundation (External organisation)
Drost, J. (Member)
2022 → …Activity: Membership › Membership of council
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ITCC (Innovative Therapies for Children with Cancer in Europe) (External organisation)
Drost, J. (Member)
2021Activity: Membership › Membership of network