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Marcel Kool

1997 …2026

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  • Advancing CNS tumor diagnostics with expanded DNA methylation-based classification

    Sill, M., Schrimpf, D., Patel, A., Sturm, D., Jäger, N., Sievers, P., Schweizer, L., Banan, R., Reuss, D., Suwala, A., Korshunov, A., Stichel, D., Wefers, A. K., Hau, A. C., Boldt, H., Harter, P. N., Abdullaev, Z., Benhamida, J., Teichmann, D. & Koch, A. & 101 others, Hench, J., Frank, S., Hasselblatt, M., Mansouri, S., Díaz de Ståhl, T., Serrano, J., Ecker, J., Selt, F., Taylor, M., Ramaswamy, V., Cavalli, F., Berghoff, A. S., Bison, B., Blattner-Johnson, M., Buchhalter, I., Buslei, R., Calaminus, G., Dikow, N., Dohmen, H., Euskirchen, P., Fleischhack, G., Gajjar, A., Gerber, N. U., Gessi, M., Gielen, G. H., Gnekow, A., Gottardo, N. G., Haberler, C., Hamelmann, S., Hans, V., Hansford, J. R., Hartmann, C., Heppner, F. L., Driever, P. H., von Hoff, K., Thomale, U. W., Tippelt, S., Frühwald, M. C., Kramm, C. M., Schüller, U., Schittenhelm, J., Schuhmann, M. U., Stein, M., Ketteler, P., Ladanyi, M., Jabado, N., Jones, B. C., Jones, C., Karajannis, M. A., Ketter, R., Kohlhof, P., Kordes, U., Reinhardt, A., Kölsche, C., Lamszus, K., Lichter, P., Maas, S. L. N., Mawrin, C., Milde, T., Mittelbronn, M., Monoranu, C. M., Mueller, W., Mynarek, M., Northcott, P. A., Pajtler, K. W., Paulus, W., Perry, A., Blümcke, I., Plate, K. H., Platten, M., Preusser, M., Pietsch, T., Prinz, M., Reifenberger, G., Kristensen, B. W., Kool, M., Hovestadt, V., Ellison, D. W., Jacques, T. S., Varlet, P., Etminan, N., Acker, T., Weller, M., White, C. L., Witt, O., Herold-Mende, C., Debus, J., Krieg, S., Wick, W., Snuderl, M., Aldape, K., Brandner, S., Hawkins, C., Horbinski, C., Thomas, C., Wesseling, P., von Deimling, A., Capper, D., Pfister, S. M., Jones, D. T. W. & Sahm, F., 9 Feb 2026, In: Cancer Cell. 44, 2, p. 340-354.e2

    Research output: Contribution to journal › Article › peer-review

    Open Access
    26 Citations (Scopus)

  • Author Correction: Multidimensional profiling of heterogeneity in supratentorial ependymomas

    Jeong, D., Danielli, S. G., Maaß, K. K., Ghasemi, D. R., Tetzlaff, S. K., Reyhan, E., Jiang, L., Katiyar, S., Sundheimer, J. K., Lo Cascio, C., Neyazi, S., de Biagi-Junior, C. A. O., Couvillon, E., Castellani, S., Pazyra-Murphy, M., Mullally, M., Dehler, M. P., Englinger, B., Nascimento, A. & Cruzeiro, G. A. V. & 19 others, Marques, J. G., Haase, R. D., Nguyen, C. M., Baumgartner, A. C., Rozowsky, J. S., Hack, O. A., Shaw, M. L., Lotsch-Gojo, D., Bruckner, K., Korshunov, A., Pfister, S. M., Kool, M., Nowakowski, T. J., Gojo, J., Baird, L., Alexandrescu, S., Pajtler, K. W., Venkataramani, V. & Filbin, M. G., May 2026, In: Nature. 653, 8115, p. E9-E9

    Research output: Contribution to journal › Comment/debate

    Open Access

  • Author Correction: Defective DNA damage repair leads to frequent catastrophic genomic events in murine and human tumors

    Ratnaparkhe, M., Wong, J. K. L., Wei, P. C., Hlevnjak, M., Kolb, T., Simovic, M., Haag, D., Paul, Y., Devens, F., Northcott, P., Jones, D. T. W., Kool, M., Jauch, A., Pastorczak, A., Mlynarski, W., Korshunov, A., Kumar, R., Downing, S. M., Pfister, S. M. & Zapatka, M. & 4 others, McKinnon, P. J., Alt, F. W., Lichter, P. & Ernst, A., 20 Apr 2026, In: Nature communications. 17, 1, 3611.

    Research output: Contribution to journal › Comment/debate

    Open Access

  • CAR T cells targeting the glycoprotein GD2 show potent antitumor efficacy in high-risk ependymoma models

    Tallon-Cobos, A. C., Vazaios, K., Waranecki, P., van Hoesel, M., Cornel, A., Schwalm, B., Mack, N., de Boed, E., van der Lugt, J., Nierkens, S., Kool, M., Hoving, E. W., Metselaar, D. S. & Hulleman, E., 16 Jan 2026, In: The Journal of clinical investigation. 136, 2

    Research output: Contribution to journal › Article › peer-review

    Open Access
    1 Citation (Scopus)

  • Co-targeting CDK4/6 and MEK reverses mesenchymal transition in therapy-refractory BRAF-altered pediatric high-grade glioma

    Mayr, L., Mager, L., Gabler-Pamer, L., Kirchhofer, D., Freund, J., Schwark, K., Lau, B., Machreich, S., Senfter, D., Neumüller, M., Lang, A., Madlener, S., Laemmerer, A., Bruckner, K., Jaunecker, C. N., Robl, B., Walter, R., Schueler, J., Peyrl, A. & Azizi, A. A. & 17 others, Dorfer, C., Roessler, K., Spiegl-Kreinecker, S., Haberler, C., Federico, A., Gopisetty, A., Schleiermacher, G., Pfister, S. M., Geoerger, B., Chesler, L., Vassal, G., Kool, M., Müllauer, L., Koschmann, C., Berger, W., Gojo, J. & Lötsch, D., Dec 2026, In: Journal of Experimental and Clinical Cancer Research. 45, 1, 154.

    Research output: Contribution to journal › Article › peer-review

    Open Access
View all 365 research outputs