@article{b5cb0ebebea948aeab2f0597c15cfc16,
title = "A Comprehensive Human Gastric Cancer Organoid Biobank Captures Tumor Subtype Heterogeneity and Enables Therapeutic Screening",
abstract = "Leung and colleagues established a biobank of patient-derived gastric cancer organoids that encompasses a diverse array of subtypes and maintained long-term similarity to the original tumors. They used the organoids to perform large-scale drug screening that identified potential target drugs and could guide patient drug selection.",
keywords = "ARHGAP fusions, biobank, drug screening, EBV genome, gastric cancer, heterogeneity, organoid culture, RHOA mutations, transcriptome sequencing, whole-exome sequencing",
author = "Yan, {Helen H.N.} and Siu, {Hoi Cheong} and Simon Law and Ho, {Siu Lun} and Yue, {Sarah S.K.} and Tsui, {Wai Yin} and Dessy Chan and Chan, {April S.} and Stephanie Ma and Lam, {Ka On} and Sina Bartfeld and Man, {Alice H.Y.} and Lee, {Bernard C.H.} and Chan, {Annie S.Y.} and Wong, {Jason W.H.} and Cheng, {Priscilla S.W.} and Chan, {Anthony K.W.} and Jiangwen Zhang and Jue Shi and Xiaodan Fan and Kwong, {Dora L.W.} and Mak, {Tak W.} and Yuen, {Siu Tsan} and Hans Clevers and Leung, {Suet Yi}",
note = "Publisher Copyright: {\textcopyright} 2018 Elsevier Inc.",
year = "2018",
month = dec,
day = "6",
doi = "10.1016/j.stem.2018.09.016",
language = "English",
volume = "23",
pages = "882--897.e11",
journal = "Cell Stem Cell",
issn = "1934-5909",
publisher = "Cell Press",
number = "6",
}