A phase 1 comparative pharmacokinetic and cardiac safety study of two intravenous formulations of CO-101 in patients with advanced solid tumors

F. E. Stuurman; M. P. Lolkema; A. D.R. Huitema; P. M.M.B. Soetekouw; H. Rosing; L. Rolfe; P. Kaur; J. H. Beijnen; H. Van Tinteren; E. E. Voest; J. H.M. Schellens

doi:10.1002/jcph.108

A phase 1 comparative pharmacokinetic and cardiac safety study of two intravenous formulations of CO-101 in patients with advanced solid tumors

F. E. Stuurman
, M. P. Lolkema
, A. D.R. Huitema
, P. M.M.B. Soetekouw
, H. Rosing
, L. Rolfe
, P. Kaur
, J. H. Beijnen
, H. Van Tinteren
, E. E. Voest
, J. H.M. Schellens

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Original language	English
Pages (from-to)	878-883
Number of pages	6
Journal	Journal of Clinical Pharmacology
Volume	53
Issue number	8
DOIs	https://doi.org/10.1002/jcph.108
Publication status	Published - Aug 2013
Externally published	Yes

Keywords

Bioequivalence
Cancer
CO-101
CP-4126
DFdC
DFdU
Formulation
Gemcitabine
Infusion
Lipid
Phase 1
Phospholipids
QT/QTC intervals

Access to Document

10.1002/jcph.108

Cite this

Stuurman, F. E., Lolkema, M. P., Huitema, A. D. R., Soetekouw, P. M. M. B., Rosing, H., Rolfe, L., Kaur, P., Beijnen, J. H., Van Tinteren, H., Voest, E. E., & Schellens, J. H. M. (2013). A phase 1 comparative pharmacokinetic and cardiac safety study of two intravenous formulations of CO-101 in patients with advanced solid tumors. Journal of Clinical Pharmacology, 53(8), 878-883. https://doi.org/10.1002/jcph.108

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keywords = "Bioequivalence, Cancer, CO-101, CP-4126, DFdC, DFdU, Formulation, Gemcitabine, Infusion, Lipid, Phase 1, Phospholipids, QT/QTC intervals",

author = "Stuurman, \{F. E.\} and Lolkema, \{M. P.\} and Huitema, \{A. D.R.\} and Soetekouw, \{P. M.M.B.\} and H. Rosing and L. Rolfe and P. Kaur and Beijnen, \{J. H.\} and \{Van Tinteren\}, H. and Voest, \{E. E.\} and Schellens, \{J. H.M.\}",

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language = "English",

volume = "53",

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Stuurman, FE, Lolkema, MP, Huitema, ADR, Soetekouw, PMMB, Rosing, H, Rolfe, L, Kaur, P, Beijnen, JH, Van Tinteren, H, Voest, EE & Schellens, JHM 2013, 'A phase 1 comparative pharmacokinetic and cardiac safety study of two intravenous formulations of CO-101 in patients with advanced solid tumors', Journal of Clinical Pharmacology, vol. 53, no. 8, pp. 878-883. https://doi.org/10.1002/jcph.108

TY - JOUR

T1 - A phase 1 comparative pharmacokinetic and cardiac safety study of two intravenous formulations of CO-101 in patients with advanced solid tumors

AU - Stuurman, F. E.

AU - Lolkema, M. P.

AU - Huitema, A. D.R.

AU - Soetekouw, P. M.M.B.

AU - Rosing, H.

AU - Rolfe, L.

AU - Kaur, P.

AU - Beijnen, J. H.

AU - Van Tinteren, H.

AU - Voest, E. E.

AU - Schellens, J. H.M.

PY - 2013/8

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KW - Bioequivalence

KW - Cancer

KW - CO-101

KW - CP-4126

KW - DFdC

KW - DFdU

KW - Formulation

KW - Gemcitabine

KW - Infusion

KW - Lipid

KW - Phase 1

KW - Phospholipids

KW - QT/QTC intervals

UR - https://www.scopus.com/pages/publications/84885061000

U2 - 10.1002/jcph.108

DO - 10.1002/jcph.108

M3 - Article

C2 - 23775853

AN - SCOPUS:84885061000

SN - 0091-2700

VL - 53

SP - 878

EP - 883

JO - Journal of Clinical Pharmacology

JF - Journal of Clinical Pharmacology

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