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Axin and hepatocellular carcinomas

Research output: Contribution to journalShort surveypeer-review

50 Citations (Scopus)

Abstract

A gene (AXIN1) encoding another component of the Wnt-signalling pathway is reported to be mutated in human tumours, underscoring the oncogenic consequences of inappropriate activation of developmental signalling pathways later in life. Inhibitors of these signals therefore represent potential agents with which to treat cancer.

Original languageEnglish
Pages (from-to)206-208
Number of pages3
JournalNature Genetics
Volume24
Issue number3
DOIs
Publication statusPublished - 2000
Externally publishedYes

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