Carcinoid in a horseshoe kidney. Morphology, immunohistochemistry, and cytogenetics

E. van den Berg; A. S.H. Gouw; J. W. Oosterhuis; S. Störkel; T. Dijkhuizen; H. J.A. Mensink; B. de Jong

doi:10.1016/0165-4608(95)00094-1

Carcinoid in a horseshoe kidney. Morphology, immunohistochemistry, and cytogenetics

E. van den Berg
, A. S.H. Gouw
, J. W. Oosterhuis
, S. Störkel
, T. Dijkhuizen
, H. J.A. Mensink
, B. de Jong

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

Renal carcinoids are very rare neoplasms. We were able to culture and subsequently karyotype a carcinoid located in the isthmus of a horseshoe kidney, which revealed the following chromosomal pattern: 47,XX,+13[8]/46,XX,t(13;14)(q31;q11.2)[5]/46,XX[2]. The DNA index was 1. Our results, compared with the sparse data from the literature, suggest that carcinoid of the kidney has no cytogenetic aberrations in common with carcinoids from other anatomical sites reported. On the other hand, numerical and structural aberrations of chromosome 13 seem to play a crucial role in the development of metanephric-derived renal tumors.

Original language	English
Pages (from-to)	95-98
Number of pages	4
Journal	Cancer Genetics and Cytogenetics
Volume	84
Issue number	2
DOIs	https://doi.org/10.1016/0165-4608(95)00094-1
Publication status	Published - 15 Oct 1995
Externally published	Yes

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title = "Carcinoid in a horseshoe kidney. Morphology, immunohistochemistry, and cytogenetics",

abstract = "Renal carcinoids are very rare neoplasms. We were able to culture and subsequently karyotype a carcinoid located in the isthmus of a horseshoe kidney, which revealed the following chromosomal pattern: 47,XX,+13[8]/46,XX,t(13;14)(q31;q11.2)[5]/46,XX[2]. The DNA index was 1. Our results, compared with the sparse data from the literature, suggest that carcinoid of the kidney has no cytogenetic aberrations in common with carcinoids from other anatomical sites reported. On the other hand, numerical and structural aberrations of chromosome 13 seem to play a crucial role in the development of metanephric-derived renal tumors.",

author = "\{van den Berg\}, E. and Gouw, \{A. S.H.\} and Oosterhuis, \{J. W.\} and S. St{\"o}rkel and T. Dijkhuizen and Mensink, \{H. J.A.\} and \{de Jong\}, B.",

year = "1995",

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doi = "10.1016/0165-4608(95)00094-1",

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TY - JOUR

T1 - Carcinoid in a horseshoe kidney. Morphology, immunohistochemistry, and cytogenetics

AU - van den Berg, E.

AU - Gouw, A. S.H.

AU - Oosterhuis, J. W.

AU - Störkel, S.

AU - Dijkhuizen, T.

AU - Mensink, H. J.A.

AU - de Jong, B.

PY - 1995/10/15

Y1 - 1995/10/15

N2 - Renal carcinoids are very rare neoplasms. We were able to culture and subsequently karyotype a carcinoid located in the isthmus of a horseshoe kidney, which revealed the following chromosomal pattern: 47,XX,+13[8]/46,XX,t(13;14)(q31;q11.2)[5]/46,XX[2]. The DNA index was 1. Our results, compared with the sparse data from the literature, suggest that carcinoid of the kidney has no cytogenetic aberrations in common with carcinoids from other anatomical sites reported. On the other hand, numerical and structural aberrations of chromosome 13 seem to play a crucial role in the development of metanephric-derived renal tumors.

AB - Renal carcinoids are very rare neoplasms. We were able to culture and subsequently karyotype a carcinoid located in the isthmus of a horseshoe kidney, which revealed the following chromosomal pattern: 47,XX,+13[8]/46,XX,t(13;14)(q31;q11.2)[5]/46,XX[2]. The DNA index was 1. Our results, compared with the sparse data from the literature, suggest that carcinoid of the kidney has no cytogenetic aberrations in common with carcinoids from other anatomical sites reported. On the other hand, numerical and structural aberrations of chromosome 13 seem to play a crucial role in the development of metanephric-derived renal tumors.

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ER -

Carcinoid in a horseshoe kidney. Morphology, immunohistochemistry, and cytogenetics

Abstract

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