Carcinoma in situ in the testis

Mikael Rørth; Ewa Rajpert-De Meyts; Lennart Andersson; Klaus Peter Dieckmann; Sophie D. Fosså; Kenneth M. Grigor; William F. Hendry; Harry W. Herr; Leendert H.J. Looijenga; J. Wolter Oosterhuis; Niels E. Skakkebaek

doi:10.1080/00365590050509896

Carcinoma in situ in the testis

Mikael Rørth, Ewa Rajpert-De Meyts, Lennart Andersson, Klaus Peter Dieckmann, Sophie D. Fosså, Kenneth M. Grigor, William F. Hendry, Harry W. Herr, Leendert H.J. Looijenga, J. Wolter Oosterhuis, Niels E. Skakkebaek

Research output: Contribution to journal › Article › peer-review

157 Citations (Scopus)

Abstract

Carcinoma in situ (CIS) of the testis is a common precursor of germ-cell tumours in adults and adolescents, with the exception of spermatocytic seminoma. This article reviews existing knowledge on the pathobiology, genetic aspects and epidemiology of CIS, discusses current hypotheses concerning pathogenesis and invasive progression of germ-cell neoplasms and provides guidelines for diagnosis and clinical management of CIS.

Original language	English
Pages (from-to)	166-186
Number of pages	21
Journal	Scandinavian Journal of Urology and Nephrology, Supplement
Volume	34
Issue number	205
DOIs	https://doi.org/10.1080/00365590050509896
Publication status	Published - 2000
Externally published	Yes

Keywords

Carcinoma in situ
Germ cell
Isochromosome i(p12)
Orchidectomy
Radiotherapy
Testicular biopsy
Testicular development
Testicular neoplasms

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10.1080/00365590050509896

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@article{6007332ed4e74f2d966fe292037b687e,

title = "Carcinoma in situ in the testis",

abstract = "Carcinoma in situ (CIS) of the testis is a common precursor of germ-cell tumours in adults and adolescents, with the exception of spermatocytic seminoma. This article reviews existing knowledge on the pathobiology, genetic aspects and epidemiology of CIS, discusses current hypotheses concerning pathogenesis and invasive progression of germ-cell neoplasms and provides guidelines for diagnosis and clinical management of CIS.",

keywords = "Carcinoma in situ, Germ cell, Isochromosome i(p12), Orchidectomy, Radiotherapy, Testicular biopsy, Testicular development, Testicular neoplasms",

author = "Mikael R{\o}rth and {Rajpert-De Meyts}, Ewa and Lennart Andersson and Dieckmann, {Klaus Peter} and Foss{\aa}, {Sophie D.} and Grigor, {Kenneth M.} and Hendry, {William F.} and Herr, {Harry W.} and Looijenga, {Leendert H.J.} and Oosterhuis, {J. Wolter} and Skakkebaek, {Niels E.}",

note = "Funding Information: The authors thank Dr G. Bosl for critical comments. Drs H. Lauke and A. F. Holstein for excellent photographs of electron-microscopic and seminthin preparations. The research summarized in this review was supported in part by the Danish Cancer Society, and other national and international organizations.",

year = "2000",

doi = "10.1080/00365590050509896",

language = "English",

volume = "34",

pages = "166--186",

journal = "Scandinavian Journal of Urology and Nephrology, Supplement",

issn = "0300-8886",

publisher = "Taylor and Francis Ltd.",

number = "205",

}

TY - JOUR

T1 - Carcinoma in situ in the testis

AU - Rørth, Mikael

AU - Rajpert-De Meyts, Ewa

AU - Andersson, Lennart

AU - Dieckmann, Klaus Peter

AU - Fosså, Sophie D.

AU - Grigor, Kenneth M.

AU - Hendry, William F.

AU - Herr, Harry W.

AU - Looijenga, Leendert H.J.

AU - Oosterhuis, J. Wolter

AU - Skakkebaek, Niels E.

N1 - Funding Information: The authors thank Dr G. Bosl for critical comments. Drs H. Lauke and A. F. Holstein for excellent photographs of electron-microscopic and seminthin preparations. The research summarized in this review was supported in part by the Danish Cancer Society, and other national and international organizations.

PY - 2000

Y1 - 2000

N2 - Carcinoma in situ (CIS) of the testis is a common precursor of germ-cell tumours in adults and adolescents, with the exception of spermatocytic seminoma. This article reviews existing knowledge on the pathobiology, genetic aspects and epidemiology of CIS, discusses current hypotheses concerning pathogenesis and invasive progression of germ-cell neoplasms and provides guidelines for diagnosis and clinical management of CIS.

AB - Carcinoma in situ (CIS) of the testis is a common precursor of germ-cell tumours in adults and adolescents, with the exception of spermatocytic seminoma. This article reviews existing knowledge on the pathobiology, genetic aspects and epidemiology of CIS, discusses current hypotheses concerning pathogenesis and invasive progression of germ-cell neoplasms and provides guidelines for diagnosis and clinical management of CIS.

KW - Carcinoma in situ

KW - Germ cell

KW - Isochromosome i(p12)

KW - Orchidectomy

KW - Radiotherapy

KW - Testicular biopsy

KW - Testicular development

KW - Testicular neoplasms

UR - http://www.scopus.com/inward/record.url?scp=4243579630&partnerID=8YFLogxK

U2 - 10.1080/00365590050509896

DO - 10.1080/00365590050509896

M3 - Article

C2 - 11144894

SN - 0300-8886

VL - 34

SP - 166

EP - 186

JO - Scandinavian Journal of Urology and Nephrology, Supplement

JF - Scandinavian Journal of Urology and Nephrology, Supplement

IS - 205

ER -

Carcinoma in situ in the testis

Abstract

Keywords

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