Cefpirome as empirical treatment for febrile neutropenia in patients with hematologic malignancies

Gert Jan Timmers; Dannis G van Vuurden; Eleonora L Swart; Alberdina M Simoons-Smit; Peter C Huijgens

Cefpirome as empirical treatment for febrile neutropenia in patients with hematologic malignancies

Gert Jan Timmers
, Dannis G van Vuurden
, Eleonora L Swart
, Alberdina M Simoons-Smit
, Peter C Huijgens

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Cefpirome, a fourth generation cephalosporin, was administered during 154 episodes of febrile neutropenia in 106 patients. We assessed the clinical efficacy of cefpirome and its activity against isolated pathogens in neutropenic patients with hematologic malignancies. In addition, the pharmacokinetics and optimal dosing regimen of cefpirome during neutropenia were investigated.

Original language	English
Pages (from-to)	1005-6
Number of pages	2
Journal	Haematologica
Volume	90
Issue number	7
Publication status	Published - Jul 2005
Externally published	Yes

Keywords

Aged
Anti-Bacterial Agents/therapeutic use
Cephalosporins/therapeutic use
Female
Fever/drug therapy
Hematologic Neoplasms/drug therapy
Humans
Male
Middle Aged
Neutropenia/drug therapy

Cite this

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title = "Cefpirome as empirical treatment for febrile neutropenia in patients with hematologic malignancies",

abstract = "Cefpirome, a fourth generation cephalosporin, was administered during 154 episodes of febrile neutropenia in 106 patients. We assessed the clinical efficacy of cefpirome and its activity against isolated pathogens in neutropenic patients with hematologic malignancies. In addition, the pharmacokinetics and optimal dosing regimen of cefpirome during neutropenia were investigated.",

keywords = "Aged, Anti-Bacterial Agents/therapeutic use, Cephalosporins/therapeutic use, Female, Fever/drug therapy, Hematologic Neoplasms/drug therapy, Humans, Male, Middle Aged, Neutropenia/drug therapy",

author = "Timmers, \{Gert Jan\} and \{van Vuurden\}, \{Dannis G\} and Swart, \{Eleonora L\} and Simoons-Smit, \{Alberdina M\} and Huijgens, \{Peter C\}",

year = "2005",

month = jul,

language = "English",

volume = "90",

pages = "1005--6",

journal = "Haematologica",

issn = "0390-6078",

publisher = "Ferrata Storti Foundation",

number = "7",

}

TY - JOUR

T1 - Cefpirome as empirical treatment for febrile neutropenia in patients with hematologic malignancies

AU - Timmers, Gert Jan

AU - van Vuurden, Dannis G

AU - Swart, Eleonora L

AU - Simoons-Smit, Alberdina M

AU - Huijgens, Peter C

PY - 2005/7

Y1 - 2005/7

N2 - Cefpirome, a fourth generation cephalosporin, was administered during 154 episodes of febrile neutropenia in 106 patients. We assessed the clinical efficacy of cefpirome and its activity against isolated pathogens in neutropenic patients with hematologic malignancies. In addition, the pharmacokinetics and optimal dosing regimen of cefpirome during neutropenia were investigated.

AB - Cefpirome, a fourth generation cephalosporin, was administered during 154 episodes of febrile neutropenia in 106 patients. We assessed the clinical efficacy of cefpirome and its activity against isolated pathogens in neutropenic patients with hematologic malignancies. In addition, the pharmacokinetics and optimal dosing regimen of cefpirome during neutropenia were investigated.

KW - Aged

KW - Anti-Bacterial Agents/therapeutic use

KW - Cephalosporins/therapeutic use

KW - Female

KW - Fever/drug therapy

KW - Hematologic Neoplasms/drug therapy

KW - Humans

KW - Male

KW - Middle Aged

KW - Neutropenia/drug therapy

M3 - Article

C2 - 15996951

SN - 0390-6078

VL - 90

SP - 1005

EP - 1006

JO - Haematologica

JF - Haematologica

IS - 7

ER -

Cefpirome as empirical treatment for febrile neutropenia in patients with hematologic malignancies

Abstract

Keywords

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