Cell biology: Ageing nucleus gets out of shape

Hannes Lans; Jan H.J. Hoeijmakers

doi:10.1038/440032a

Cell biology: Ageing nucleus gets out of shape

Hannes Lans
, Jan H.J. Hoeijmakers

Research output: Contribution to journal › Short survey › peer-review

51 Citations (Scopus)

Abstract

In certain premature-ageing syndromes, the architecture of the cell nucleus is abnormal. An animal model shows similar malformations during normal ageing, corroborating the idea that genome instability underlies ageing.

Original language	English
Pages (from-to)	32-34
Number of pages	3
Journal	Nature
Volume	440
Issue number	7080
DOIs	https://doi.org/10.1038/440032a
Publication status	Published - 2 Mar 2006
Externally published	Yes

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title = "Cell biology: Ageing nucleus gets out of shape",

abstract = "In certain premature-ageing syndromes, the architecture of the cell nucleus is abnormal. An animal model shows similar malformations during normal ageing, corroborating the idea that genome instability underlies ageing.",

author = "Hannes Lans and Hoeijmakers, \{Jan H.J.\}",

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T1 - Cell biology

T2 - Ageing nucleus gets out of shape

AU - Lans, Hannes

AU - Hoeijmakers, Jan H.J.

PY - 2006/3/2

Y1 - 2006/3/2

N2 - In certain premature-ageing syndromes, the architecture of the cell nucleus is abnormal. An animal model shows similar malformations during normal ageing, corroborating the idea that genome instability underlies ageing.

AB - In certain premature-ageing syndromes, the architecture of the cell nucleus is abnormal. An animal model shows similar malformations during normal ageing, corroborating the idea that genome instability underlies ageing.

UR - https://www.scopus.com/pages/publications/33644765799

U2 - 10.1038/440032a

DO - 10.1038/440032a

M3 - Short survey

C2 - 16511477

AN - SCOPUS:33644765799

SN - 0028-0836

VL - 440

SP - 32

EP - 34

JO - Nature

JF - Nature

IS - 7080

ER -

Cell biology: Ageing nucleus gets out of shape

Abstract

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