Chromosome segregation: taking the passenger seat

Gerben Vader; Susanne M A Lens

doi:10.1016/j.cub.2010.09.037

Chromosome segregation: taking the passenger seat

Gerben Vader, Susanne M A Lens

Research output: Contribution to journal › Article › peer-review

Abstract

The chromosomal passenger complex (CPC) is a major regulator of mitotic and meiotic chromosome segregation. Three recent papers now elucidate the mechanisms that determine the localization of the CPC to the inner centromere.

Original language	English
Pages (from-to)	R879-81
Journal	Current Biology
Volume	20
Issue number	20
DOIs	https://doi.org/10.1016/j.cub.2010.09.037
Publication status	Published - 26 Oct 2010
Externally published	Yes

Keywords

Aurora Kinases
Centromere/metabolism
Chromosomal Proteins, Non-Histone/metabolism
Chromosome Segregation/physiology
Microtubule-Associated Proteins/metabolism
Models, Biological
Multiprotein Complexes/genetics
Phosphorylation
Protein Serine-Threonine Kinases/metabolism

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10.1016/j.cub.2010.09.037

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title = "Chromosome segregation: taking the passenger seat",

abstract = "The chromosomal passenger complex (CPC) is a major regulator of mitotic and meiotic chromosome segregation. Three recent papers now elucidate the mechanisms that determine the localization of the CPC to the inner centromere.",

keywords = "Aurora Kinases, Centromere/metabolism, Chromosomal Proteins, Non-Histone/metabolism, Chromosome Segregation/physiology, Microtubule-Associated Proteins/metabolism, Models, Biological, Multiprotein Complexes/genetics, Phosphorylation, Protein Serine-Threonine Kinases/metabolism",

author = "Gerben Vader and Lens, {Susanne M A}",

year = "2010",

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day = "26",

doi = "10.1016/j.cub.2010.09.037",

language = "English",

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journal = "Current Biology",

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T1 - Chromosome segregation

T2 - taking the passenger seat

AU - Vader, Gerben

AU - Lens, Susanne M A

PY - 2010/10/26

Y1 - 2010/10/26

N2 - The chromosomal passenger complex (CPC) is a major regulator of mitotic and meiotic chromosome segregation. Three recent papers now elucidate the mechanisms that determine the localization of the CPC to the inner centromere.

AB - The chromosomal passenger complex (CPC) is a major regulator of mitotic and meiotic chromosome segregation. Three recent papers now elucidate the mechanisms that determine the localization of the CPC to the inner centromere.

KW - Aurora Kinases

KW - Centromere/metabolism

KW - Chromosomal Proteins, Non-Histone/metabolism

KW - Chromosome Segregation/physiology

KW - Microtubule-Associated Proteins/metabolism

KW - Models, Biological

KW - Multiprotein Complexes/genetics

KW - Phosphorylation

KW - Protein Serine-Threonine Kinases/metabolism

U2 - 10.1016/j.cub.2010.09.037

DO - 10.1016/j.cub.2010.09.037

M3 - Article

C2 - 20971428

SN - 0960-9822

VL - 20

SP - R879-81

JO - Current Biology

JF - Current Biology

IS - 20

ER -

Chromosome segregation: taking the passenger seat

Abstract

Keywords

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