Clinical Characteristics of Invasive Fungal Infections in Pediatric Oncology Patients with Solid Tumors

Veerle J. Ruijters, Natanja Oosterom, Madeleine E.M. Van Der Perk, Tom F.W. Wolfs, Annelot J.M. Meijer, Marry M. Van Den Heuvel-Eibrink, Martine Van Grotel

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Invasive fungal infections (IFIs) are an important cause of morbidity and mortality in children with cancer. Studies on the clinical characteristics of IFI in children with solid tumors are limited. This Dutch retrospective cohort study reviewed the medical records of 61 children with solid tumors to analyze the clinical characteristics during their full treatment period. Seven IFI episodes were reported in 6/61 patients (10%), all diagnosed with intermediate-risk or high-risk Wilms tumor or neuroblastoma. Larger studies are necessary to reveal the determinants of IFI in this group of patients and the value of fungal prophylaxis.

Original languageEnglish
Pages (from-to)e408-e413
JournalJournal of Pediatric Hematology/Oncology
Volume43
Issue number3
DOIs
Publication statusPublished - Apr 2021

Keywords

  • clinical characteristics
  • frequency
  • invasive fungal infections
  • pediatric oncology patients

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