Combination therapy with cisplatin: Modulation of activity and tumour sensitivity

H. J. Guchelaar; D. R.A. Uges; E. G.E. de Vries; J. W. Oosterhuis; N. H. Mulder

doi:10.1016/S0936-6555(05)81134-3

Combination therapy with cisplatin: Modulation of activity and tumour sensitivity

H. J. Guchelaar
, D. R.A. Uges
, E. G.E. de Vries
, J. W. Oosterhuis
, N. H. Mulder

Research output: Contribution to journal › Review article › peer-review

11 Citations (Scopus)

Abstract

Although cisplatin is applied with success in clinical oncology, this success is limited because some cancers are initially unresponsive to cisplatin or become so during treatment. In this review, some strategies to overcome this problem are discussed. Among these are combination with the differentiation inducing agent, retinoic acid, combination with radiotherapy, and the use of hyperthermia.

Original language	English
Pages (from-to)	388-393
Number of pages	6
Journal	Clinical Oncology
Volume	4
Issue number	6
DOIs	https://doi.org/10.1016/S0936-6555(05)81134-3
Publication status	Published - 1992
Externally published	Yes

Keywords

Chemoradiotherapy
Cisplatin
Differentiation induction
Hyperthermia
Retinoids

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10.1016/S0936-6555(05)81134-3

Cite this

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title = "Combination therapy with cisplatin: Modulation of activity and tumour sensitivity",

abstract = "Although cisplatin is applied with success in clinical oncology, this success is limited because some cancers are initially unresponsive to cisplatin or become so during treatment. In this review, some strategies to overcome this problem are discussed. Among these are combination with the differentiation inducing agent, retinoic acid, combination with radiotherapy, and the use of hyperthermia.",

keywords = "Chemoradiotherapy, Cisplatin, Differentiation induction, Hyperthermia, Retinoids",

author = "Guchelaar, \{H. J.\} and Uges, \{D. R.A.\} and \{de Vries\}, \{E. G.E.\} and Oosterhuis, \{J. W.\} and Mulder, \{N. H.\}",

year = "1992",

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language = "English",

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pages = "388--393",

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T1 - Combination therapy with cisplatin

T2 - Modulation of activity and tumour sensitivity

AU - Guchelaar, H. J.

AU - Uges, D. R.A.

AU - de Vries, E. G.E.

AU - Oosterhuis, J. W.

AU - Mulder, N. H.

PY - 1992

Y1 - 1992

N2 - Although cisplatin is applied with success in clinical oncology, this success is limited because some cancers are initially unresponsive to cisplatin or become so during treatment. In this review, some strategies to overcome this problem are discussed. Among these are combination with the differentiation inducing agent, retinoic acid, combination with radiotherapy, and the use of hyperthermia.

AB - Although cisplatin is applied with success in clinical oncology, this success is limited because some cancers are initially unresponsive to cisplatin or become so during treatment. In this review, some strategies to overcome this problem are discussed. Among these are combination with the differentiation inducing agent, retinoic acid, combination with radiotherapy, and the use of hyperthermia.

KW - Chemoradiotherapy

KW - Cisplatin

KW - Differentiation induction

KW - Hyperthermia

KW - Retinoids

UR - https://www.scopus.com/pages/publications/0026948534

U2 - 10.1016/S0936-6555(05)81134-3

DO - 10.1016/S0936-6555(05)81134-3

M3 - Review article

C2 - 1340781

AN - SCOPUS:0026948534

SN - 0936-6555

VL - 4

SP - 388

EP - 393

JO - Clinical Oncology

JF - Clinical Oncology

IS - 6

ER -

Combination therapy with cisplatin: Modulation of activity and tumour sensitivity

Abstract

Keywords

Access to Document

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