Congenital mesoblastic nephroma 50 years after its recognition: A narrative review

S. L. Gooskens, M. E. Houwing, G. M. Vujanic, J. S. Dome, T. Diertens, A. Coulomb-l'Herminé, J. Godzinski, K. Pritchard-Jones, N. Graf, M. M. van den Heuvel-Eibrink

Research output: Contribution to journalReview articlepeer-review

80 Citations (Scopus)

Abstract

Congenital mesoblastic nephroma (CMN) is a rare pediatric renal tumor with low malignant potential that most commonly occurs early in infancy. Treatment strategies are based on the few published CMN series, while a significant number of CMN patients have been described in case reports. The aim of this narrative review was to create an up-to-date overview of the literature. Complete surgical removal is curative in most cases. The risk of treatment-related mortality (both surgery- and chemotherapy-related) is relatively high in the first weeks of life, indicating that these young patients deserve special attention with respect to timing and type of treatment.

Original languageEnglish
Article numbere26437
JournalPediatric Blood and Cancer
Volume64
Issue number7
DOIs
Publication statusPublished - Jul 2017

Keywords

  • clinical characteristics
  • congenital mesoblastic nephroma
  • genetics
  • histology
  • infancy
  • outcome
  • renal tumor
  • review
  • treatment

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