Consequences of diagnosing a tumor predisposition syndrome in children with cancer: A literature review

Floor A M Postema; Saskia M J Hopman; Raoul C Hennekam; Hans Merks

doi:10.1002/pbc.26718

Consequences of diagnosing a tumor predisposition syndrome in children with cancer: A literature review

Floor A M Postema, Saskia M J Hopman, Raoul C Hennekam, Merks

Research output: Contribution to journal › Review article › peer-review

16 Citations (Scopus)

Abstract

Up to 8.5% of children with cancer have a genetic cause for their cancer: a tumor predisposition syndrome (TPS). Diagnosing a TPS is of great importance, as it may have major consequences for clinical care. Patients with TPSs require specific monitoring and management. We present an overview of the cancer-related and noncancer-related consequences for the 36 most common TPSs.

Original language	English
Journal	Pediatric blood & cancer
Volume	65
Issue number	1
DOIs	https://doi.org/10.1002/pbc.26718
Publication status	Published - Aug 2017
Externally published	Yes

Keywords

Adolescent
Child
Child, Preschool
Female
Genetic Predisposition to Disease
Humans
Infant
Male
Neoplastic Syndromes, Hereditary/genetics

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10.1002/pbc.26718

Cite this

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title = "Consequences of diagnosing a tumor predisposition syndrome in children with cancer: A literature review",

abstract = "Up to 8.5% of children with cancer have a genetic cause for their cancer: a tumor predisposition syndrome (TPS). Diagnosing a TPS is of great importance, as it may have major consequences for clinical care. Patients with TPSs require specific monitoring and management. We present an overview of the cancer-related and noncancer-related consequences for the 36 most common TPSs.",

keywords = "Adolescent, Child, Child, Preschool, Female, Genetic Predisposition to Disease, Humans, Infant, Male, Neoplastic Syndromes, Hereditary/genetics",

author = "Postema, {Floor A M} and Hopman, {Saskia M J} and Hennekam, {Raoul C} and Merks",

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AU - Postema, Floor A M

AU - Hopman, Saskia M J

AU - Hennekam, Raoul C

AU - Merks, null

PY - 2017/8

Y1 - 2017/8

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AB - Up to 8.5% of children with cancer have a genetic cause for their cancer: a tumor predisposition syndrome (TPS). Diagnosing a TPS is of great importance, as it may have major consequences for clinical care. Patients with TPSs require specific monitoring and management. We present an overview of the cancer-related and noncancer-related consequences for the 36 most common TPSs.

KW - Adolescent

KW - Child

KW - Child, Preschool

KW - Female

KW - Genetic Predisposition to Disease

KW - Humans

KW - Infant

KW - Male

KW - Neoplastic Syndromes, Hereditary/genetics

U2 - 10.1002/pbc.26718

DO - 10.1002/pbc.26718

M3 - Review article

C2 - 28834056

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VL - 65

JO - Pediatric blood & cancer

JF - Pediatric blood & cancer

IS - 1

ER -

Consequences of diagnosing a tumor predisposition syndrome in children with cancer: A literature review

Abstract

Keywords

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