Keyphrases
Acute Lymphoblastic Leukemia
100%
Vulnerability
100%
KMT2A
100%
CRISPR-Cas9 Library
100%
Library Screening
100%
KMT2A Gene
33%
Therapeutic Target
16%
Leukemia
16%
Cell Line Models
16%
Targeted Therapy
16%
Therapeutic Strategies
16%
Putative Drug Targets
16%
Epigenetic Modification
16%
Leukemia Cell Lines
16%
Acute Lymphoblastic Leukemia Cells
16%
Genetic Lesions
16%
Epigenetic Regulators
16%
Gene Expression Profile
16%
Epigenome
16%
Mutational Landscape
16%
Gene Drive
16%
BMPR2
16%
Unfavorable Prognostic Factors
16%
Kinome
16%
Chromosomal Translocation
16%
Receptor-interacting Protein Kinase 1 (RIPK1)
16%
Differential Gene Expression
16%
Screening Approach
16%
Aberrant Gene Expression
16%
SgRNA Library
16%
MBD3
16%
Small Guide RNA
16%
CRISPR-Cas9 Knockout
16%
Genetic Dependency
16%
ARID4B
16%
Biochemistry, Genetics and Molecular Biology
CRISPR/Cas9
100%
KMT2A
100%
Genetics
25%
Epigenetics
25%
Wild Type
12%
Gene Expression
12%
Kinase
12%
Phosphotransferase
12%
Epigenome
12%
Gene Drive
12%
Chromosomal Translocation
12%
Kinome
12%
Guide RNA
12%
Differential Gene Expression
12%
Bone Morphogenetic Protein Receptor Type 2
12%
MBD3
12%