Cytogenetics as a tool in the histologic subclassification of chondrosarcomas

Trijnie Dijkhuizen; Eva van den Berg; Willemina M. Molenaar; J. Wolter Oosterhuis; Anke Dam; Janneke Wiersema; Heimen Schraffordt Koops; Bauke de Jong

doi:10.1016/0165-4608(94)90457-X

Cytogenetics as a tool in the histologic subclassification of chondrosarcomas

Trijnie Dijkhuizen
, Eva van den Berg
, Willemina M. Molenaar
, J. Wolter Oosterhuis
, Anke Dam
, Janneke Wiersema
, Heimen Schraffordt Koops
, Bauke de Jong

Research output: Contribution to journal › Article › peer-review

32 Citations (Scopus)

Abstract

Chondrosarcomas are a heterogeneous group of bone neoplasms of which the basic neoplastic tissue is cartilaginous. Frequently the histologic diagnosis and grading of chondrosarcomas is difficult and the histologic appearance does not always reflect the biologic behavior of these tumors. Therefore, it is important to find other parameters that can be of help in the proper diagnosing and grading of these neoplasms. To this end, we attempted to correlate the chromosomal pattern of chondrosarcomas to their histologic subtypes and grades. The cytogenetic analysis of two intermediate-grade chondrosarcomas of bone, and a review of the literature, are presented.

Original language	English
Pages (from-to)	100-105
Number of pages	6
Journal	Cancer Genetics and Cytogenetics
Volume	76
Issue number	2
DOIs	https://doi.org/10.1016/0165-4608(94)90457-X
Publication status	Published - Sept 1994
Externally published	Yes

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@article{1c155245fe214cef94a9c715aa27d95e,

title = "Cytogenetics as a tool in the histologic subclassification of chondrosarcomas",

abstract = "Chondrosarcomas are a heterogeneous group of bone neoplasms of which the basic neoplastic tissue is cartilaginous. Frequently the histologic diagnosis and grading of chondrosarcomas is difficult and the histologic appearance does not always reflect the biologic behavior of these tumors. Therefore, it is important to find other parameters that can be of help in the proper diagnosing and grading of these neoplasms. To this end, we attempted to correlate the chromosomal pattern of chondrosarcomas to their histologic subtypes and grades. The cytogenetic analysis of two intermediate-grade chondrosarcomas of bone, and a review of the literature, are presented.",

author = "Trijnie Dijkhuizen and \{van den Berg\}, Eva and Molenaar, \{Willemina M.\} and Oosterhuis, \{J. Wolter\} and Anke Dam and Janneke Wiersema and \{Schraffordt Koops\}, Heimen and \{de Jong\}, Bauke",

year = "1994",

month = sep,

doi = "10.1016/0165-4608(94)90457-X",

language = "English",

volume = "76",

pages = "100--105",

journal = "Cancer Genetics and Cytogenetics",

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TY - JOUR

T1 - Cytogenetics as a tool in the histologic subclassification of chondrosarcomas

AU - Dijkhuizen, Trijnie

AU - van den Berg, Eva

AU - Molenaar, Willemina M.

AU - Oosterhuis, J. Wolter

AU - Dam, Anke

AU - Wiersema, Janneke

AU - Schraffordt Koops, Heimen

AU - de Jong, Bauke

PY - 1994/9

Y1 - 1994/9

N2 - Chondrosarcomas are a heterogeneous group of bone neoplasms of which the basic neoplastic tissue is cartilaginous. Frequently the histologic diagnosis and grading of chondrosarcomas is difficult and the histologic appearance does not always reflect the biologic behavior of these tumors. Therefore, it is important to find other parameters that can be of help in the proper diagnosing and grading of these neoplasms. To this end, we attempted to correlate the chromosomal pattern of chondrosarcomas to their histologic subtypes and grades. The cytogenetic analysis of two intermediate-grade chondrosarcomas of bone, and a review of the literature, are presented.

AB - Chondrosarcomas are a heterogeneous group of bone neoplasms of which the basic neoplastic tissue is cartilaginous. Frequently the histologic diagnosis and grading of chondrosarcomas is difficult and the histologic appearance does not always reflect the biologic behavior of these tumors. Therefore, it is important to find other parameters that can be of help in the proper diagnosing and grading of these neoplasms. To this end, we attempted to correlate the chromosomal pattern of chondrosarcomas to their histologic subtypes and grades. The cytogenetic analysis of two intermediate-grade chondrosarcomas of bone, and a review of the literature, are presented.

UR - https://www.scopus.com/pages/publications/0028127312

U2 - 10.1016/0165-4608(94)90457-X

DO - 10.1016/0165-4608(94)90457-X

M3 - Article

C2 - 7923056

AN - SCOPUS:0028127312

SN - 0165-4608

VL - 76

SP - 100

EP - 105

JO - Cancer Genetics and Cytogenetics

JF - Cancer Genetics and Cytogenetics

IS - 2

ER -

Cytogenetics as a tool in the histologic subclassification of chondrosarcomas

Abstract

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