Cytogenetics of 12 cases of renal adenocarcinoma

Bauke de Jong; J. Wolter Oosterhuis; Vera J.S. Idenburg; Sergio M.M.J. Castedo; Anke Dam; Han J.A. Mensink

doi:10.1016/0165-4608(88)90092-1

Cytogenetics of 12 cases of renal adenocarcinoma

Bauke de Jong
, J. Wolter Oosterhuis
, Vera J.S. Idenburg
, Sergio M.M.J. Castedo
, Anke Dam
, Han J.A. Mensink

Research output: Contribution to journal › Article › peer-review

61 Citations (Scopus)

Abstract

The cytogenetics of 12 cases of renal adenocarcinoma are presented. Clonal abnormalities were found in nine patients. Worth mentioning are abnormalities of the X chromosome (1 ×) and the chromosomes #1(3 ×), #3(3 ×), #7(4 ×), #8(4 ×), and #14(2 ×). From our data and data from the literature it appeared that the chromosomal regions 3p11-p21, 1q21, 14q22, and Xp11 are important for the oncogenesis of renal cell carcinoma as well as increased dosage of chromosome #7 and loss or abnormalities of chromosomes #8 and #14.

Original language	English
Pages (from-to)	53-61
Number of pages	9
Journal	Cancer Genetics and Cytogenetics
Volume	30
Issue number	1
DOIs	https://doi.org/10.1016/0165-4608(88)90092-1
Publication status	Published - Jan 1988
Externally published	Yes

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@article{c81e62faf45042188d754b75a682001b,

title = "Cytogenetics of 12 cases of renal adenocarcinoma",

abstract = "The cytogenetics of 12 cases of renal adenocarcinoma are presented. Clonal abnormalities were found in nine patients. Worth mentioning are abnormalities of the X chromosome (1 ×) and the chromosomes \#1(3 ×), \#3(3 ×), \#7(4 ×), \#8(4 ×), and \#14(2 ×). From our data and data from the literature it appeared that the chromosomal regions 3p11-p21, 1q21, 14q22, and Xp11 are important for the oncogenesis of renal cell carcinoma as well as increased dosage of chromosome \#7 and loss or abnormalities of chromosomes \#8 and \#14.",

author = "\{de Jong\}, Bauke and Oosterhuis, \{J. Wolter\} and Idenburg, \{Vera J.S.\} and Castedo, \{Sergio M.M.J.\} and Anke Dam and Mensink, \{Han J.A.\}",

note = "Funding Information: Supported by The Netherlands Cancer l:oundatiou, the Jan Korllelis de Cock Sticbtin!\textasciitilde{}, and the Stichting Kinderoncologie Groniugen. The authors thank Mentje Dijkstra for typing tim manuscript.",

year = "1988",

month = jan,

doi = "10.1016/0165-4608(88)90092-1",

language = "English",

volume = "30",

pages = "53--61",

journal = "Cancer Genetics and Cytogenetics",

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T1 - Cytogenetics of 12 cases of renal adenocarcinoma

AU - de Jong, Bauke

AU - Oosterhuis, J. Wolter

AU - Idenburg, Vera J.S.

AU - Castedo, Sergio M.M.J.

AU - Dam, Anke

AU - Mensink, Han J.A.

N1 - Funding Information: Supported by The Netherlands Cancer l:oundatiou, the Jan Korllelis de Cock Sticbtin!~, and the Stichting Kinderoncologie Groniugen. The authors thank Mentje Dijkstra for typing tim manuscript.

PY - 1988/1

Y1 - 1988/1

N2 - The cytogenetics of 12 cases of renal adenocarcinoma are presented. Clonal abnormalities were found in nine patients. Worth mentioning are abnormalities of the X chromosome (1 ×) and the chromosomes #1(3 ×), #3(3 ×), #7(4 ×), #8(4 ×), and #14(2 ×). From our data and data from the literature it appeared that the chromosomal regions 3p11-p21, 1q21, 14q22, and Xp11 are important for the oncogenesis of renal cell carcinoma as well as increased dosage of chromosome #7 and loss or abnormalities of chromosomes #8 and #14.

AB - The cytogenetics of 12 cases of renal adenocarcinoma are presented. Clonal abnormalities were found in nine patients. Worth mentioning are abnormalities of the X chromosome (1 ×) and the chromosomes #1(3 ×), #3(3 ×), #7(4 ×), #8(4 ×), and #14(2 ×). From our data and data from the literature it appeared that the chromosomal regions 3p11-p21, 1q21, 14q22, and Xp11 are important for the oncogenesis of renal cell carcinoma as well as increased dosage of chromosome #7 and loss or abnormalities of chromosomes #8 and #14.

UR - https://www.scopus.com/pages/publications/0023838928

U2 - 10.1016/0165-4608(88)90092-1

DO - 10.1016/0165-4608(88)90092-1

M3 - Article

C2 - 3422048

AN - SCOPUS:0023838928

SN - 0165-4608

VL - 30

SP - 53

EP - 61

JO - Cancer Genetics and Cytogenetics

JF - Cancer Genetics and Cytogenetics

IS - 1

ER -

Cytogenetics of 12 cases of renal adenocarcinoma

Abstract

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