Cytogenetics of carcinoma in situ of the testis

Anne Marie Vos; J. Wolter Oosterhuis; Bauke de Jong; Janneke Buist; Heimen Schraffordt Koops

doi:10.1016/0165-4608(90)90011-X

Cytogenetics of carcinoma in situ of the testis

Anne Marie Vos
, J. Wolter Oosterhuis
, Bauke de Jong
, Janneke Buist
, Heimen Schraffordt Koops

Research output: Contribution to journal › Article › peer-review

71 Citations (Scopus)

Abstract

Carcinoma in situ (CIS) of the testis is the precursor lesion of most testicular germ cell tumors (TGCTs). Karyotyping of CIS is important for a better understanding of the pathogenesis of TGCTs and the progression to invasive cancer. We karyotyped three cases of CIS. All three cases showed a numerical abnormal chromosomal pattern. In one case, two copies of the germ cell tumor marker i(12p) were found.

Original language	English
Pages (from-to)	75-81
Number of pages	7
Journal	Cancer Genetics and Cytogenetics
Volume	46
Issue number	1
DOIs	https://doi.org/10.1016/0165-4608(90)90011-X
Publication status	Published - May 1990
Externally published	Yes

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title = "Cytogenetics of carcinoma in situ of the testis",

abstract = "Carcinoma in situ (CIS) of the testis is the precursor lesion of most testicular germ cell tumors (TGCTs). Karyotyping of CIS is important for a better understanding of the pathogenesis of TGCTs and the progression to invasive cancer. We karyotyped three cases of CIS. All three cases showed a numerical abnormal chromosomal pattern. In one case, two copies of the germ cell tumor marker i(12p) were found.",

author = "Vos, \{Anne Marie\} and Oosterhuis, \{J. Wolter\} and \{de Jong\}, Bauke and Janneke Buist and Koops, \{Heimen Schraffordt\}",

year = "1990",

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AU - Vos, Anne Marie

AU - Oosterhuis, J. Wolter

AU - de Jong, Bauke

AU - Buist, Janneke

AU - Koops, Heimen Schraffordt

PY - 1990/5

Y1 - 1990/5

N2 - Carcinoma in situ (CIS) of the testis is the precursor lesion of most testicular germ cell tumors (TGCTs). Karyotyping of CIS is important for a better understanding of the pathogenesis of TGCTs and the progression to invasive cancer. We karyotyped three cases of CIS. All three cases showed a numerical abnormal chromosomal pattern. In one case, two copies of the germ cell tumor marker i(12p) were found.

AB - Carcinoma in situ (CIS) of the testis is the precursor lesion of most testicular germ cell tumors (TGCTs). Karyotyping of CIS is important for a better understanding of the pathogenesis of TGCTs and the progression to invasive cancer. We karyotyped three cases of CIS. All three cases showed a numerical abnormal chromosomal pattern. In one case, two copies of the germ cell tumor marker i(12p) were found.

UR - https://www.scopus.com/pages/publications/0025330183

U2 - 10.1016/0165-4608(90)90011-X

DO - 10.1016/0165-4608(90)90011-X

M3 - Article

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VL - 46

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JO - Cancer Genetics and Cytogenetics

JF - Cancer Genetics and Cytogenetics

IS - 1

ER -

Cytogenetics of carcinoma in situ of the testis

Abstract

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