Determinants of erythrocyte methotrexate polyglutamate levels in rheumatoid arthritis

Keyphrases

• Methotrexate 100%
• Rheumatoid Arthritis 100%
• Erythrocytes 100%
• Methotrexate Polyglutamates 100%
• Validation Cohort 10%
• Rotterdam 7%
• Genotype 7%
• Erythrocyte Folate 7%
• Folylpolyglutamate Synthetase 7%
• Netherlands 3%
• Genetic Factors 3%
• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 3%
• Combined Cohort 3%
• Personalized Treatment 3%
• Regression Analysis 3%
• Negatively Associated 3%
• Clinical Factors 3%
• High Age 3%
• Folate Levels 3%
• High Concentration 3%
• Longitudinal Cohort 3%
• Inter-patient Variability 3%
• Folate Status 3%
• Biochemical Factors 3%
• Low-dose Methotrexate 3%
• Early Arthritis 3%

Immunology and Microbiology

• Methotrexate 100%
• Inflammatory Arthritis 100%
• Erythrocyte 100%
• Wild Type 6%
• Drug Megadose 3%
• Arthritis 3%
• Heredity 3%
• Low Drug Dose 3%
• Liquid Chromatography Mass Spectrometry 3%

Biochemistry, Genetics and Molecular Biology

• Methotrexate 100%
• Wild Type 6%
• Genotyping 6%
• Folic Acid 6%
• Folylpolyglutamate Synthase 6%
• Prospective Study 3%
• Genetic Determinism 3%
• Drug Megadose 3%
• Cohort Study 3%
• Low Drug Dose 3%
• Liquid Chromatography-Mass Spectrometry 3%