Een vaginale zwelling en bloedverlies bij een peuter

Translated title of the contribution: A toddler with a vaginal mass and blood loss; the rhabdomyosarcoma

N Pleunis, W B Breunis, J H M Merks, A E Bouwma, J W van der Steeg

Research output: Contribution to journalArticlepeer-review


BACKGROUND: The differential diagnosis of vaginal blood loss in childhood is broad, and includes irritation of the mucous membranes, trauma, tumours, foreign bodies and sexual abuse. Physical and additional examination is often initially difficult; however, prompt detection of a rhabdomyosarcoma, a soft-tissue tumour principally diagnosed in childhood, is vitally important.

CASE DESCRIPTION: A 3-year-old girl with a history of vaginal blood loss and an introital mass was referred to the gynaecologist. Treatment with oestriol and triamcinolone cream did not lead to healing. Pathological examination of a biopsy taken under general anaesthetic indicated an embryonic rhabdomyosarcoma. Chemotherapy, surgical resection and brachytherapy lead to persistent remission of the tumour.

CONCLUSION: Because rhabdomyosarcoma is rare and can present atypically, diagnosis can be delayed. Early recognition is, however, essential and this condition should be placed high in the differential diagnosis by vaginal blood loss or vaginal abnormality in childhood.

Translated title of the contributionA toddler with a vaginal mass and blood loss; the rhabdomyosarcoma
Original languageDutch
Pages (from-to)D1674
JournalNederlands tijdschrift voor geneeskunde
Publication statusPublished - 2017
Externally publishedYes


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