Epidemiology of Cerebral Palsy in Adulthood: A Systematic Review and Meta-analysis of the Most Frequently Studied Outcomes: A Systematic Review and Meta-analysis of the Most Frequently Studied Outcomes

Marloes van Gorp, Sander R. Hilberink, Suzie Noten, Joyce L. Benner, Henk J. Stam, Wilma M.A. van der Slot, Marij E. Roebroeck

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

Objective: To describe the epidemiology of health status, impairments, activities and participation in adults with cerebral palsy (CP). Data Sources: Embase, MEDLINE, Web of Science, PsycINFO, Cumulative Index to Nursing and Allied Health, Cochrane, and Google Scholar were searched for 3 themes (“cerebral palsy,” “adult,” and “outcome assessment”) in literature published between January 2000 and December 2018. Study Selection: Full-article peer-reviewed English journal articles on descriptive, observational, or experimental studies describing the most studied outcomes in adults with CP (n≥25, age≥18y) were included. Studies were included in the analyses if frequently studied outcomes were described in at least 3 studies using similar methods of assessment. Data Extraction: Data were extracted independently by 2 authors from 65 articles (total N=28,429) using a standardized score sheet. Data Synthesis: Meta-analyses revealed that overall, on average 65.1% (95% confidence interval [CI], 55.1-74.5) of adults with CP experienced pain, 57.9% (95% CI, 51.1-64.6) were ambulant, 65.5% (95% CI, 61.2-69.7) had little or no limitation in manual ability, 18.2% (95% CI, 10.6-27.2) had tertiary education, 39.2% (95% CI, 31.5;47.1) were employed, and 29.3% (95% CI, 9.0-55.3) lived independently. In adults without intellectual disability, proportions of individuals who were ambulant (72.6% [95% CI, 58.8-84.5]) and lived independently (90.0% [95% CI, 83.8-94.9]) were higher (P=.014 and P
Original languageEnglish
Pages (from-to)1041-1052
Number of pages12
JournalArchives of Physical Medicine and Rehabilitation
Volume101
Issue number6
DOIs
Publication statusPublished - 1 Jun 2020

Keywords

  • Adult
  • Cerebral palsy
  • Epidemiology
  • Health
  • Meta-analysis
  • Rehabilitation
  • Systematic review

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