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Exhaled nitric oxide: A novel biomarker of adverse respiratory health effects in epidemiological studies

  • Jan G.C. van Amsterdam
  • , Stefan Nierkens
  • , Sjef G. Vos
  • , Antoon Opperhuizen
  • , Henkvan Loveren
  • , Peter A. Steerenberg

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)

Abstract

The sampling of exhaled breath is a noninvasive procedure that can be performed easily in adults, children, and patients with respiratory disease. Several studies have demonstrated increased exhaled nitric oxide in patients with pulmonary disease, including asthma. In addition, exhaled nitric oxide may be an elegant tool for monitoring of environmental health effects of air pollution and the prevalence of atopy in epidemiological surveys. Recent literature about exhaled nitric oxide is presented in this article. Technical, physiological, and behavioral confounding factors of exhaled nitric oxide measurement are outlined.

Original languageEnglish
Pages (from-to)418-423
Number of pages6
JournalArchives of Environmental Health
Volume55
Issue number6
DOIs
Publication statusPublished - 2000
Externally publishedYes

Keywords

  • Air pollution
  • Allergy
  • Asthma
  • Biomarker
  • Exhaled air
  • Nitric oxide

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