FLT3 N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis

Axel Hyrenius-Wittsten; Mattias Pilheden; Antoni Falqués-Costa; Mia Eriksson; Helena Sturesson; Pauline Schneider; Priscilla Wander; Cristian Garcia-Ruiz; Jian Liu; Helena Ågerstam; Anne Hultquist; Henrik Lilljebjörn; Ronald W. Stam; Marcus Järås; Anna K. Hagström-Andersson

doi:10.1038/s41375-019-0465-1

FLT3 ^N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis

Axel Hyrenius-Wittsten
, Mattias Pilheden
, Antoni Falqués-Costa
, Mia Eriksson
, Helena Sturesson
, Pauline Schneider
, Priscilla Wander
, Cristian Garcia-Ruiz
, Jian Liu
, Helena Ågerstam
, Anne Hultquist
, Henrik Lilljebjörn
, Ronald W. Stam
, Marcus Järås
, Anna K. Hagström-Andersson

Group Stam

Research output: Contribution to journal › Letter › peer-review

4 Citations (Scopus)

Original language	English
Pages (from-to)	2310-2314
Number of pages	5
Journal	Leukemia
Volume	33
Issue number	9
DOIs	https://doi.org/10.1038/s41375-019-0465-1
Publication status	Published - 1 Sept 2019

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10.1038/s41375-019-0465-1

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Hyrenius-Wittsten, A., Pilheden, M., Falqués-Costa, A., Eriksson, M., Sturesson, H., Schneider, P., Wander, P., Garcia-Ruiz, C., Liu, J., Ågerstam, H., Hultquist, A., Lilljebjörn, H., Stam, R. W., Järås, M., & Hagström-Andersson, A. K. (2019). FLT3 ^N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis. Leukemia, 33(9), 2310-2314. https://doi.org/10.1038/s41375-019-0465-1

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title = "FLT3 N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis",

author = "Axel Hyrenius-Wittsten and Mattias Pilheden and Antoni Falqu{\'e}s-Costa and Mia Eriksson and Helena Sturesson and Pauline Schneider and Priscilla Wander and Cristian Garcia-Ruiz and Jian Liu and Helena {\AA}gerstam and Anne Hultquist and Henrik Lilljebj{\"o}rn and Stam, \{Ronald W.\} and Marcus J{\"a}r{\aa}s and Hagstr{\"o}m-Andersson, \{Anna K.\}",

note = "Funding Information: Acknowledgements This work was supported by The Swedish Childhood Cancer Foundation, The Swedish Cancer Society, The Swedish Research Council, The Knut and Alice Wallenberg Foundation, BioCARE, The Crafoord Foundation, The Per-Eric and Ulla Schyberg Foundation, The Nilsson-Ehle Donations, The Wiberg Foundation, and Governmental Funding of Clinical Research within the National Health Service. Work performed at the Center for Translational Genomics, Lund University has been funded by Medical Faculty Lund University, Region Sk{\aa}ne and Science for Life Laboratory, Sweden.",

year = "2019",

month = sep,

day = "1",

doi = "10.1038/s41375-019-0465-1",

language = "English",

volume = "33",

pages = "2310--2314",

journal = "Leukemia",

issn = "0887-6924",

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number = "9",

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Hyrenius-Wittsten, A, Pilheden, M, Falqués-Costa, A, Eriksson, M, Sturesson, H, Schneider, P, Wander, P, Garcia-Ruiz, C, Liu, J, Ågerstam, H, Hultquist, A, Lilljebjörn, H, Stam, RW, Järås, M & Hagström-Andersson, AK 2019, 'FLT3 ^N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis', Leukemia, vol. 33, no. 9, pp. 2310-2314. https://doi.org/10.1038/s41375-019-0465-1

TY - JOUR

T1 - FLT3 N676K drives acute myeloid leukemia in a xenograft model of KMT2A-MLLT3 leukemogenesis

AU - Hyrenius-Wittsten, Axel

AU - Pilheden, Mattias

AU - Falqués-Costa, Antoni

AU - Eriksson, Mia

AU - Sturesson, Helena

AU - Schneider, Pauline

AU - Wander, Priscilla

AU - Garcia-Ruiz, Cristian

AU - Liu, Jian

AU - Ågerstam, Helena

AU - Hultquist, Anne

AU - Lilljebjörn, Henrik

AU - Stam, Ronald W.

AU - Järås, Marcus

AU - Hagström-Andersson, Anna K.

N1 - Funding Information: Acknowledgements This work was supported by The Swedish Childhood Cancer Foundation, The Swedish Cancer Society, The Swedish Research Council, The Knut and Alice Wallenberg Foundation, BioCARE, The Crafoord Foundation, The Per-Eric and Ulla Schyberg Foundation, The Nilsson-Ehle Donations, The Wiberg Foundation, and Governmental Funding of Clinical Research within the National Health Service. Work performed at the Center for Translational Genomics, Lund University has been funded by Medical Faculty Lund University, Region Skåne and Science for Life Laboratory, Sweden.

PY - 2019/9/1

Y1 - 2019/9/1

UR - https://www.scopus.com/pages/publications/85063950491

U2 - 10.1038/s41375-019-0465-1

DO - 10.1038/s41375-019-0465-1

M3 - Letter

C2 - 30953031

AN - SCOPUS:85063950491

SN - 0887-6924

VL - 33

SP - 2310

EP - 2314

JO - Leukemia

JF - Leukemia

IS - 9

ER -