Functional analysis of Peutz-Jeghers mutations reveals that the LKB1 C-terminal region exerts a crucial role in regulating both the AMPK pathway and the cell polarity

Christelle Forcet, Sandrine Etienne-Manneville, Hélène Gaude, Laurence Fournier, Sébastien Debilly, Marko Salmi, Annette Baas, Sylviane Olschwang, Hans Clevers, Marc Billaud

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Biochemistry, Genetics and Molecular Biology