Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer

Ramprasath Venkatachalam, Marjolijn J L Ligtenberg, Nicoline Hoogerbrugge, Hans K Schackert, Heike Görgens, Marc-Manuel Hahn, Eveline J Kamping, Lilian Vreede, Eveline Hoenselaar, Erica van der Looij, Monique Goossens, Mike Churchman, Luis Carvajal-Carmona, Ian P M Tomlinson, Diederik R H de Bruijn, Ad Geurts Van Kessel, Roland P Kuiper

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)
Original languageEnglish
Pages (from-to)2221-4
Number of pages4
JournalGastroenterology
Volume139
Issue number6
DOIs
Publication statusPublished - Dec 2010
Externally publishedYes

Keywords

  • Age of Onset
  • Colorectal Neoplasms/genetics
  • Gene Silencing/physiology
  • Genetic Predisposition to Disease
  • Germ-Line Mutation
  • Humans
  • Pedigree
  • Receptor-Like Protein Tyrosine Phosphatases, Class 3/genetics

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