Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer

Ramprasath Venkatachalam; Marjolijn J L Ligtenberg; Nicoline Hoogerbrugge; Hans K Schackert; Heike Görgens; Marc-Manuel Hahn; Eveline J Kamping; Lilian Vreede; Eveline Hoenselaar; Erica van der Looij; Monique Goossens; Mike Churchman; Luis Carvajal-Carmona; Ian P M Tomlinson; Diederik R H de Bruijn; Ad Geurts Van Kessel; Roland P Kuiper

doi:10.1053/j.gastro.2010.08.063

Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer

Ramprasath Venkatachalam
, Marjolijn J L Ligtenberg
, Nicoline Hoogerbrugge
, Hans K Schackert
, Heike Görgens
, Marc-Manuel Hahn
, Eveline J Kamping
, Lilian Vreede
, Eveline Hoenselaar
, Erica van der Looij
, Monique Goossens
, Mike Churchman
, Luis Carvajal-Carmona
, Ian P M Tomlinson
, Diederik R H de Bruijn
, Ad Geurts Van Kessel
, Roland P Kuiper

Research output: Contribution to journal › Article › peer-review

41 Citations (Scopus)

Original language	English
Pages (from-to)	2221-4
Number of pages	4
Journal	Gastroenterology
Volume	139
Issue number	6
DOIs	https://doi.org/10.1053/j.gastro.2010.08.063
Publication status	Published - Dec 2010
Externally published	Yes

Keywords

Age of Onset
Colorectal Neoplasms/genetics
Gene Silencing/physiology
Genetic Predisposition to Disease
Germ-Line Mutation
Humans
Pedigree
Receptor-Like Protein Tyrosine Phosphatases, Class 3/genetics

Access to Document

10.1053/j.gastro.2010.08.063

Cite this

Venkatachalam, R., Ligtenberg, M. J. L., Hoogerbrugge, N., Schackert, H. K., Görgens, H., Hahn, M.-M., Kamping, E. J., Vreede, L., Hoenselaar, E., van der Looij, E., Goossens, M., Churchman, M., Carvajal-Carmona, L., Tomlinson, I. P. M., de Bruijn, D. R. H., Van Kessel, A. G., & Kuiper, R. P. (2010). Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer. Gastroenterology, 139(6), 2221-4. https://doi.org/10.1053/j.gastro.2010.08.063

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title = "Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer",

keywords = "Age of Onset, Colorectal Neoplasms/genetics, Gene Silencing/physiology, Genetic Predisposition to Disease, Germ-Line Mutation, Humans, Pedigree, Receptor-Like Protein Tyrosine Phosphatases, Class 3/genetics",

author = "Ramprasath Venkatachalam and Ligtenberg, \{Marjolijn J L\} and Nicoline Hoogerbrugge and Schackert, \{Hans K\} and Heike G{\"o}rgens and Marc-Manuel Hahn and Kamping, \{Eveline J\} and Lilian Vreede and Eveline Hoenselaar and \{van der Looij\}, Erica and Monique Goossens and Mike Churchman and Luis Carvajal-Carmona and Tomlinson, \{Ian P M\} and \{de Bruijn\}, \{Diederik R H\} and \{Van Kessel\}, \{Ad Geurts\} and Kuiper, \{Roland P\}",

year = "2010",

month = dec,

doi = "10.1053/j.gastro.2010.08.063",

language = "English",

volume = "139",

pages = "2221--4",

journal = "Gastroenterology",

issn = "0016-5085",

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}

Venkatachalam, R, Ligtenberg, MJL, Hoogerbrugge, N, Schackert, HK, Görgens, H, Hahn, M-M, Kamping, EJ, Vreede, L, Hoenselaar, E, van der Looij, E, Goossens, M, Churchman, M, Carvajal-Carmona, L, Tomlinson, IPM, de Bruijn, DRH, Van Kessel, AG & Kuiper, RP 2010, 'Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer', Gastroenterology, vol. 139, no. 6, pp. 2221-4. https://doi.org/10.1053/j.gastro.2010.08.063

TY - JOUR

T1 - Germline epigenetic silencing of the tumor suppressor gene PTPRJ in early-onset familial colorectal cancer

AU - Venkatachalam, Ramprasath

AU - Ligtenberg, Marjolijn J L

AU - Hoogerbrugge, Nicoline

AU - Schackert, Hans K

AU - Görgens, Heike

AU - Hahn, Marc-Manuel

AU - Kamping, Eveline J

AU - Vreede, Lilian

AU - Hoenselaar, Eveline

AU - van der Looij, Erica

AU - Goossens, Monique

AU - Churchman, Mike

AU - Carvajal-Carmona, Luis

AU - Tomlinson, Ian P M

AU - de Bruijn, Diederik R H

AU - Van Kessel, Ad Geurts

AU - Kuiper, Roland P

PY - 2010/12

Y1 - 2010/12

KW - Age of Onset

KW - Colorectal Neoplasms/genetics

KW - Gene Silencing/physiology

KW - Genetic Predisposition to Disease

KW - Germ-Line Mutation

KW - Humans

KW - Pedigree

KW - Receptor-Like Protein Tyrosine Phosphatases, Class 3/genetics

UR - https://www.scopus.com/pages/publications/78649715850

U2 - 10.1053/j.gastro.2010.08.063

DO - 10.1053/j.gastro.2010.08.063

M3 - Article

C2 - 21036128

SN - 0016-5085

VL - 139

SP - 2221

EP - 2224

JO - Gastroenterology

JF - Gastroenterology

IS - 6

ER -