In vitro glucocorticoid resistance in childhood leukemia correlates with receptor affinity determined at 37 degrees C, but not with affinity determined at room temperature

E G Haarman, G J L Kaspers, R Pieters, M M A Rottier, M L Den Boer, G E Janka-Schaub, A J P Veerman

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)
Original languageEnglish
Pages (from-to)1882-4
Number of pages3
Issue number9
Publication statusPublished - Sept 2002
Externally publishedYes


  • Acute Disease
  • Antineoplastic Agents, Hormonal/metabolism
  • Bone Marrow/chemistry
  • Child
  • Dexamethasone/metabolism
  • Drug Resistance, Neoplasm
  • Humans
  • In Vitro Techniques
  • Leukemia, Myeloid/blood
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma/blood
  • Receptors, Glucocorticoid/metabolism
  • Temperature

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