Infant T-cell acute lymphoblastic leukaemia with t(6;7) (TCRB-MYB) translocation

Pemantah Sandheeah Ramdeny; Khushnuma Mullanfroze; Paola de Lorenzo; Maria Grazia Valsecchi; Jules Meijerink; Rob Pieters; Andre Baruchel; Ajay Vora

doi:10.1111/bjh.17609

Infant T-cell acute lymphoblastic leukaemia with t(6;7) (TCRB-MYB) translocation

Pemantah Sandheeah Ramdeny
, Khushnuma Mullanfroze
, Paola de Lorenzo
, Maria Grazia Valsecchi
, Jules Meijerink
, Rob Pieters
, Andre Baruchel
, Ajay Vora

Group Pieters

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

T-ALL is rare in infancy with only 10 (1.5%) of 651 patients of that subtype in the Interfant-06 infant ALL trial. We report 3 cases of t(6;7) (TCR/MYB) infant T-cell Acute Lymphoblastic Leukaemia who appear to have a distinct clinical presentation with CNS disease and refractory disease or late relapse.

Original language	English
Pages (from-to)	613-616
Number of pages	4
Journal	British journal of haematology
Volume	194
Issue number	3
DOIs	https://doi.org/10.1111/bjh.17609
Publication status	Published - Aug 2021

Keywords

T-Acute Lymphoblastic Leukaemia
infant

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10.1111/bjh.17609

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title = "Infant T-cell acute lymphoblastic leukaemia with t(6;7) (TCRB-MYB) translocation",

abstract = "T-ALL is rare in infancy with only 10 (1.5\%) of 651 patients of that subtype in the Interfant-06 infant ALL trial. We report 3 cases of t(6;7) (TCR/MYB) infant T-cell Acute Lymphoblastic Leukaemia who appear to have a distinct clinical presentation with CNS disease and refractory disease or late relapse.",

keywords = "T-Acute Lymphoblastic Leukaemia, infant",

author = "Ramdeny, \{Pemantah Sandheeah\} and Khushnuma Mullanfroze and \{de Lorenzo\}, Paola and \{Grazia Valsecchi\}, Maria and Jules Meijerink and Rob Pieters and Andre Baruchel and Ajay Vora",

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year = "2021",

month = aug,

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T1 - Infant T-cell acute lymphoblastic leukaemia with t(6;7) (TCRB-MYB) translocation

AU - Ramdeny, Pemantah Sandheeah

AU - Mullanfroze, Khushnuma

AU - de Lorenzo, Paola

AU - Grazia Valsecchi, Maria

AU - Meijerink, Jules

AU - Pieters, Rob

AU - Baruchel, Andre

AU - Vora, Ajay

PY - 2021/8

Y1 - 2021/8

N2 - T-ALL is rare in infancy with only 10 (1.5%) of 651 patients of that subtype in the Interfant-06 infant ALL trial. We report 3 cases of t(6;7) (TCR/MYB) infant T-cell Acute Lymphoblastic Leukaemia who appear to have a distinct clinical presentation with CNS disease and refractory disease or late relapse.

AB - T-ALL is rare in infancy with only 10 (1.5%) of 651 patients of that subtype in the Interfant-06 infant ALL trial. We report 3 cases of t(6;7) (TCR/MYB) infant T-cell Acute Lymphoblastic Leukaemia who appear to have a distinct clinical presentation with CNS disease and refractory disease or late relapse.

KW - T-Acute Lymphoblastic Leukaemia

KW - infant

UR - https://www.scopus.com/pages/publications/85109309307

U2 - 10.1111/bjh.17609

DO - 10.1111/bjh.17609

M3 - Article

C2 - 34212378

AN - SCOPUS:85109309307

SN - 0007-1048

VL - 194

SP - 613

EP - 616

JO - British journal of haematology

JF - British journal of haematology

IS - 3

ER -

Infant T-cell acute lymphoblastic leukaemia with t(6;7) (TCRB-MYB) translocation

Abstract

Keywords

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