Keyphrases
Pediatric
100%
Acute Lymphoblastic Leukemia
100%
Irinotecan
100%
Xenograft Mouse Model
100%
Disease Remission
100%
Leukemia
42%
Leukemia Cell Lines
42%
Acute Lymphoblastic Leukemia Cells
42%
Infant Acute Lymphoblastic Leukemia
28%
Camptothecin
28%
SN-38
28%
Pediatric Tumors
14%
Hematological Malignancies
14%
Clinically Significant
14%
Patient-derived Xenograft
14%
Cell Line Models
14%
Dismal Prognosis
14%
Therapeutic Strategies
14%
Monotherapy
14%
Active Metabolite
14%
Prodrug
14%
Engraftment
14%
Antileukemic Activity
14%
Preclinical Evaluation
14%
Childhood Acute Lymphoblastic Leukemia
14%
Drug Screen
14%
Mouse Xenograft
14%
Chromosomal Translocation
14%
Highly Aggressive
14%
MLL Gene
14%
Chemotherapeutic Regimens
14%
On-state Current
14%
Drug Repurposing
14%
Nanomolar Concentrations
14%
10-HCPT
14%
Ethyl
14%
Anti-leukemia
14%
KMT2A Gene
14%
Alkaloids
14%
Clinically Approved Drugs
14%
Repurposing Approaches
14%
Clinical Transition
14%
Medicine and Dentistry
Pediatrics
100%
Acute Lymphoblastic Leukemia
100%
Xenograft
100%
Spontaneous Remission
100%
Irinotecan
100%
Leukemia
30%
Leukemia Cell Line
23%
In Vitro
15%
Camptothecin
15%
SN-38
15%
Solid Malignant Neoplasm
7%
Clinical Trial
7%
Engraftment
7%
Hematologic Malignancy
7%
Chromosome Translocation
7%
Monotherapy
7%
Prodrug
7%
Drug Repositioning
7%
Active Metabolite
7%
Pharmacology, Toxicology and Pharmaceutical Science
Mouse Model
100%
Remission
100%
Acute Lymphoblastic Leukemia
100%
Irinotecan
100%
Leukemia
30%
Camptothecin
15%
Clinical Trial
7%
Solid Malignant Neoplasm
7%
Monotherapy
7%
Active Metabolite
7%
Prodrug
7%
Hematologic Malignancy
7%
Chromosome Translocation
7%
Drug Repositioning
7%