Karyotyping and DNA flow cytometry of an orchidoblastoma

J. Wolter Oosterhuis, Sérgio M.M.J. Castedo, Bauke de Jong, Raquel Seruca, Janneke Buist, Heimen Schraffordt Koops, J. Bert Leeuw

Research output: Contribution to journalArticlepeer-review

25 Citations (Scopus)


The first karyotype of an orchidoblastoma is described. The most striking finding is the absence of the i(12p) marker chromosome, considered specific for testicular germ cell tumors of adults. Differences between infantile and adult testicular germ cell tumors are discussed, as are features that infantile testicular germ cell tumors have in common with extragonadal germ cell tumors.

Original languageEnglish
Pages (from-to)7-11
Number of pages5
JournalCancer Genetics and Cytogenetics
Issue number1
Publication statusPublished - Nov 1988
Externally publishedYes


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