Lack of asparagine depletion in the cerebrospinal fluid after one intravenous dose of PEG-asparaginase: a window study at initial diagnosis of childhood ALL

I M Appel, J P V Pinheiro, M L den Boer, C Lanvers, N C M Reniers, J Boos, R Pieters

Research output: Contribution to journalArticlepeer-review

30 Citations (Scopus)
Original languageEnglish
Pages (from-to)2254-6
Number of pages3
Issue number11
Publication statusPublished - Nov 2003
Externally publishedYes


  • Antineoplastic Agents/administration & dosage
  • Asparaginase/administration & dosage
  • Asparagine/cerebrospinal fluid
  • Child
  • Humans
  • Injections, Intravenous
  • Metabolic Clearance Rate
  • Polyethylene Glycols/administration & dosage
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma/cerebrospinal fluid
  • Time Factors

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