Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis (The American Journal of Human Genetics

Despoina Manousaki; Tom Dudding; Simon Haworth; Yi Hsiang Hsu; Ching Ti Liu; Carolina Medina-Gómez; Trudy Voortman; Nathalie van der Velde; Håkan Melhus; Cassianne Robinson-Cohen; Diana L. Cousminer; Maria Nethander; Liesbeth Vandenput; Raymond Noordam; Vincenzo Forgetta; Celia M.T. Greenwood; Mary L. Biggs; Bruce M. Psaty; Jerome I. Rotter; Babette S. Zemel; Jonathan A. Mitchell; Bruce Taylor; Mattias Lorentzon; Magnus Karlsson; Vincent V.W. Jaddoe; Henning Tiemeier; Natalia Campos-Obando; Oscar H. Franco; Andre G. Utterlinden; Linda Broer; Natasja M. van Schoor; Annelies C. Ham; M. Arfan Ikram; David Karasik; Renée de Mutsert; Frits R. Rosendaal; Martin den Heijer; Thomas J. Wang; Lars Lind; Eric S. Orwoll; Dennis O. Mook-Kanamori; Karl Michaëlsson; Bryan Kestenbaum; Claes Ohlsson; Dan Mellström; Lisette C.P.G.M. de Groot; Struan F.A. Grant; Douglas P. Kiel; M. Carola Zillikens; Fernando Rivadeneira; Stephen Sawcer; Nicholas J. Timpson; J. Brent Richards

doi:10.1016/j.ajhg.2018.11.010

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis (The American Journal of Human Genetics

Despoina Manousaki, Tom Dudding, Simon Haworth, Yi Hsiang Hsu, Ching Ti Liu, Carolina Medina-Gómez, Trudy Voortman, Nathalie van der Velde, Håkan Melhus, Cassianne Robinson-Cohen, Diana L. Cousminer, Maria Nethander, Liesbeth Vandenput, Raymond Noordam, Vincenzo Forgetta, Celia M.T. Greenwood, Mary L. Biggs, Bruce M. Psaty, Jerome I. Rotter, Babette S. ZemelJonathan A. Mitchell, Bruce Taylor, Mattias Lorentzon, Magnus Karlsson, Vincent V.W. Jaddoe, Henning Tiemeier, Natalia Campos-Obando, Oscar H. Franco, Andre G. Utterlinden, Linda Broer, Natasja M. van Schoor, Annelies C. Ham, M. Arfan Ikram, David Karasik, Renée de Mutsert, Frits R. Rosendaal, Martin den Heijer, Thomas J. Wang, Lars Lind, Eric S. Orwoll, Dennis O. Mook-Kanamori, Karl Michaëlsson, Bryan Kestenbaum, Claes Ohlsson, Dan Mellström, Lisette C.P.G.M. de Groot, Struan F.A. Grant, Douglas P. Kiel, M. Carola Zillikens, Fernando Rivadeneira, Stephen Sawcer, Nicholas J. Timpson, J. Brent Richards

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Research output: Contribution to journal › Comment/debate

6 Citations (Scopus)

Abstract

(The American Journal of Human Genetics 101, 227–238; August 3, 2017) The codon position p.Asp120Asp appearing in the abstract and in the first paragraph of the Results section is incorrect. The correct position is p.Asp353Asp. The authors apologize for this error and thank Dr. Michael Levine for bringing it to the attention of the authors.

Original language	English
Pages (from-to)	1053
Number of pages	1
Journal	American Journal of Human Genetics
Volume	103
Issue number	6
DOIs	https://doi.org/10.1016/j.ajhg.2018.11.010
Publication status	Published - 6 Dec 2018

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10.1016/j.ajhg.2018.11.010

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Manousaki, D., Dudding, T., Haworth, S., Hsu, Y. H., Liu, C. T., Medina-Gómez, C., Voortman, T., van der Velde, N., Melhus, H., Robinson-Cohen, C., Cousminer, D. L., Nethander, M., Vandenput, L., Noordam, R., Forgetta, V., Greenwood, C. M. T., Biggs, M. L., Psaty, B. M., Rotter, J. I., ... Richards, J. B. (2018). Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis (The American Journal of Human Genetics. American Journal of Human Genetics, 103(6), 1053. https://doi.org/10.1016/j.ajhg.2018.11.010

@article{1adab8208b1d46b2813c047222814390,

title = "Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis (The American Journal of Human Genetics",

abstract = "(The American Journal of Human Genetics 101, 227–238; August 3, 2017) The codon position p.Asp120Asp appearing in the abstract and in the first paragraph of the Results section is incorrect. The correct position is p.Asp353Asp. The authors apologize for this error and thank Dr. Michael Levine for bringing it to the attention of the authors.",

author = "Despoina Manousaki and Tom Dudding and Simon Haworth and Hsu, {Yi Hsiang} and Liu, {Ching Ti} and Carolina Medina-G{\'o}mez and Trudy Voortman and {van der Velde}, Nathalie and H{\aa}kan Melhus and Cassianne Robinson-Cohen and Cousminer, {Diana L.} and Maria Nethander and Liesbeth Vandenput and Raymond Noordam and Vincenzo Forgetta and Greenwood, {Celia M.T.} and Biggs, {Mary L.} and Psaty, {Bruce M.} and Rotter, {Jerome I.} and Zemel, {Babette S.} and Mitchell, {Jonathan A.} and Bruce Taylor and Mattias Lorentzon and Magnus Karlsson and Jaddoe, {Vincent V.W.} and Henning Tiemeier and Natalia Campos-Obando and Franco, {Oscar H.} and Utterlinden, {Andre G.} and Linda Broer and {van Schoor}, {Natasja M.} and Ham, {Annelies C.} and Ikram, {M. Arfan} and David Karasik and {de Mutsert}, Ren{\'e}e and Rosendaal, {Frits R.} and {den Heijer}, Martin and Wang, {Thomas J.} and Lars Lind and Orwoll, {Eric S.} and Mook-Kanamori, {Dennis O.} and Karl Micha{\"e}lsson and Bryan Kestenbaum and Claes Ohlsson and Dan Mellstr{\"o}m and {de Groot}, {Lisette C.P.G.M.} and Grant, {Struan F.A.} and Kiel, {Douglas P.} and Zillikens, {M. Carola} and Fernando Rivadeneira and Stephen Sawcer and Timpson, {Nicholas J.} and Richards, {J. Brent}",

note = "Publisher Copyright: {\textcopyright} 2018 American Society of Human Genetics",

year = "2018",

month = dec,

day = "6",

doi = "10.1016/j.ajhg.2018.11.010",

language = "English",

volume = "103",

pages = "1053",

journal = "American Journal of Human Genetics",

issn = "0002-9297",

publisher = "Cell Press",

number = "6",

}

Manousaki, D, Dudding, T, Haworth, S, Hsu, YH, Liu, CT, Medina-Gómez, C, Voortman, T, van der Velde, N, Melhus, H, Robinson-Cohen, C, Cousminer, DL, Nethander, M, Vandenput, L, Noordam, R, Forgetta, V, Greenwood, CMT, Biggs, ML, Psaty, BM, Rotter, JI, Zemel, BS, Mitchell, JA, Taylor, B, Lorentzon, M, Karlsson, M, Jaddoe, VVW, Tiemeier, H, Campos-Obando, N, Franco, OH, Utterlinden, AG, Broer, L, van Schoor, NM, Ham, AC, Ikram, MA, Karasik, D, de Mutsert, R, Rosendaal, FR, den Heijer, M, Wang, TJ, Lind, L, Orwoll, ES, Mook-Kanamori, DO, Michaëlsson, K, Kestenbaum, B, Ohlsson, C, Mellström, D, de Groot, LCPGM, Grant, SFA, Kiel, DP, Zillikens, MC, Rivadeneira, F, Sawcer, S, Timpson, NJ & Richards, JB 2018, 'Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis (The American Journal of Human Genetics', American Journal of Human Genetics, vol. 103, no. 6, pp. 1053. https://doi.org/10.1016/j.ajhg.2018.11.010

TY - JOUR

T1 - Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis (The American Journal of Human Genetics

AU - Manousaki, Despoina

AU - Dudding, Tom

AU - Haworth, Simon

AU - Hsu, Yi Hsiang

AU - Liu, Ching Ti

AU - Medina-Gómez, Carolina

AU - Voortman, Trudy

AU - van der Velde, Nathalie

AU - Melhus, Håkan

AU - Robinson-Cohen, Cassianne

AU - Cousminer, Diana L.

AU - Nethander, Maria

AU - Vandenput, Liesbeth

AU - Noordam, Raymond

AU - Forgetta, Vincenzo

AU - Greenwood, Celia M.T.

AU - Biggs, Mary L.

AU - Psaty, Bruce M.

AU - Rotter, Jerome I.

AU - Zemel, Babette S.

AU - Mitchell, Jonathan A.

AU - Taylor, Bruce

AU - Lorentzon, Mattias

AU - Karlsson, Magnus

AU - Jaddoe, Vincent V.W.

AU - Tiemeier, Henning

AU - Campos-Obando, Natalia

AU - Franco, Oscar H.

AU - Utterlinden, Andre G.

AU - Broer, Linda

AU - van Schoor, Natasja M.

AU - Ham, Annelies C.

AU - Ikram, M. Arfan

AU - Karasik, David

AU - de Mutsert, Renée

AU - Rosendaal, Frits R.

AU - den Heijer, Martin

AU - Wang, Thomas J.

AU - Lind, Lars

AU - Orwoll, Eric S.

AU - Mook-Kanamori, Dennis O.

AU - Michaëlsson, Karl

AU - Kestenbaum, Bryan

AU - Ohlsson, Claes

AU - Mellström, Dan

AU - de Groot, Lisette C.P.G.M.

AU - Grant, Struan F.A.

AU - Kiel, Douglas P.

AU - Zillikens, M. Carola

AU - Rivadeneira, Fernando

AU - Sawcer, Stephen

AU - Timpson, Nicholas J.

AU - Richards, J. Brent

PY - 2018/12/6

Y1 - 2018/12/6

N2 - (The American Journal of Human Genetics 101, 227–238; August 3, 2017) The codon position p.Asp120Asp appearing in the abstract and in the first paragraph of the Results section is incorrect. The correct position is p.Asp353Asp. The authors apologize for this error and thank Dr. Michael Levine for bringing it to the attention of the authors.

AB - (The American Journal of Human Genetics 101, 227–238; August 3, 2017) The codon position p.Asp120Asp appearing in the abstract and in the first paragraph of the Results section is incorrect. The correct position is p.Asp353Asp. The authors apologize for this error and thank Dr. Michael Levine for bringing it to the attention of the authors.

UR - http://www.scopus.com/inward/record.url?scp=85057004601&partnerID=8YFLogxK

U2 - 10.1016/j.ajhg.2018.11.010

DO - 10.1016/j.ajhg.2018.11.010

M3 - Comment/debate

C2 - 30526863

AN - SCOPUS:85057004601

SN - 0002-9297

VL - 103

SP - 1053

JO - American Journal of Human Genetics

JF - American Journal of Human Genetics

IS - 6

ER -

Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis (The American Journal of Human Genetics

Abstract

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