Malignant ectomesenchymoma in children: The European pediatric Soft tissue sarcoma Study Group experience

Giuseppe Maria Milano; Daniel Orbach; Michela Casanova; Pablo Berlanga; Reineke A. Schoot; Nadege Corradini; Bernadette Brennan; Gema L. Ramirez-Villar; Lisa Lyngsie Hjalgrim; Max M. van Noesel; Rita Alaggio; Andrea Ferrari

doi:10.1002/pbc.30116

Malignant ectomesenchymoma in children: The European pediatric Soft tissue sarcoma Study Group experience

Giuseppe Maria Milano, Daniel Orbach, Michela Casanova, Pablo Berlanga, Reineke A. Schoot, Nadege Corradini, Bernadette Brennan, Gema L. Ramirez-Villar, Lisa Lyngsie Hjalgrim, Max M. van Noesel, Rita Alaggio, Andrea Ferrari

Group van Noesel

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Malignant ectomesenchymoma (MEM) is an extremely rare soft tissue tumor typical of young children, currently included in the category of skeletal muscle malignancies and characterized by a neuroblastic component. This study describes a series of 10 patients prospectively registered in the European paediatric Soft tissue sarcoma Study Group (EpSSG) database Of the 10 cases, seven had an initial local diagnosis of rhabdomyosarcoma. All patients received chemotherapy according to rhabdomyosarcoma strategy, four had radiotherapy. Overall, six patients were alive in first remission, two in second remission and one after second tumor. Only the patient with initially metastatic tumor died of disease.

Original language	English
Pages (from-to)	e30116
Journal	Pediatric Blood and Cancer
Volume	70
Issue number	2
DOIs	https://doi.org/10.1002/pbc.30116
Publication status	Published - Feb 2023

Keywords

children
EpSSG
malignant ectomesenchymoma
outcome
treatment
Sarcoma/therapy
Humans
European People
Child, Preschool
Muscle Neoplasms
Rhabdomyosarcoma/therapy
Child
Soft Tissue Neoplasms/therapy

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Milano, G. M., Orbach, D., Casanova, M., Berlanga, P., Schoot, R. A., Corradini, N., Brennan, B., Ramirez-Villar, G. L., Lyngsie Hjalgrim, L., van Noesel, M. M., Alaggio, R., & Ferrari, A. (2023). Malignant ectomesenchymoma in children: The European pediatric Soft tissue sarcoma Study Group experience. Pediatric Blood and Cancer, 70(2), e30116. https://doi.org/10.1002/pbc.30116

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title = "Malignant ectomesenchymoma in children: The European pediatric Soft tissue sarcoma Study Group experience",

abstract = "Malignant ectomesenchymoma (MEM) is an extremely rare soft tissue tumor typical of young children, currently included in the category of skeletal muscle malignancies and characterized by a neuroblastic component. This study describes a series of 10 patients prospectively registered in the European paediatric Soft tissue sarcoma Study Group (EpSSG) database Of the 10 cases, seven had an initial local diagnosis of rhabdomyosarcoma. All patients received chemotherapy according to rhabdomyosarcoma strategy, four had radiotherapy. Overall, six patients were alive in first remission, two in second remission and one after second tumor. Only the patient with initially metastatic tumor died of disease.",

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author = "Milano, {Giuseppe Maria} and Daniel Orbach and Michela Casanova and Pablo Berlanga and Schoot, {Reineke A.} and Nadege Corradini and Bernadette Brennan and Ramirez-Villar, {Gema L.} and {Lyngsie Hjalgrim}, Lisa and {van Noesel}, {Max M.} and Rita Alaggio and Andrea Ferrari",

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doi = "10.1002/pbc.30116",

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Milano, GM, Orbach, D, Casanova, M, Berlanga, P, Schoot, RA, Corradini, N, Brennan, B, Ramirez-Villar, GL, Lyngsie Hjalgrim, L, van Noesel, MM, Alaggio, R & Ferrari, A 2023, 'Malignant ectomesenchymoma in children: The European pediatric Soft tissue sarcoma Study Group experience', Pediatric Blood and Cancer, vol. 70, no. 2, pp. e30116. https://doi.org/10.1002/pbc.30116

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AU - Milano, Giuseppe Maria

AU - Orbach, Daniel

AU - Casanova, Michela

AU - Berlanga, Pablo

AU - Schoot, Reineke A.

AU - Corradini, Nadege

AU - Brennan, Bernadette

AU - Ramirez-Villar, Gema L.

AU - Lyngsie Hjalgrim, Lisa

AU - van Noesel, Max M.

AU - Alaggio, Rita

AU - Ferrari, Andrea

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AB - Malignant ectomesenchymoma (MEM) is an extremely rare soft tissue tumor typical of young children, currently included in the category of skeletal muscle malignancies and characterized by a neuroblastic component. This study describes a series of 10 patients prospectively registered in the European paediatric Soft tissue sarcoma Study Group (EpSSG) database Of the 10 cases, seven had an initial local diagnosis of rhabdomyosarcoma. All patients received chemotherapy according to rhabdomyosarcoma strategy, four had radiotherapy. Overall, six patients were alive in first remission, two in second remission and one after second tumor. Only the patient with initially metastatic tumor died of disease.

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KW - Muscle Neoplasms

KW - Rhabdomyosarcoma/therapy

KW - Child

KW - Soft Tissue Neoplasms/therapy

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KW - children

KW - malignant ectomesenchymoma

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Malignant ectomesenchymoma in children: The European pediatric Soft tissue sarcoma Study Group experience

Abstract

Keywords

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