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Microarray image denoising using a two-stage multiresolution technique

  • Hara Stefanou
  • , Thanasis Margaritis
  • , Dimitris Kafetzopoulos
  • , Konstantinos Marias
  • , Panagiotis Tsakalides

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

8 Citations (Scopus)

Abstract

DNA microarrays have demonstrated an excellent potential in correlating specific gene expression profiles to specific conditions. However, they are affected by inherent noise. This paper presents a two-stage approach for noise removal that processes the additive and the multiplicative noise component. The proposed approach first decomposes the signal by a multiresolution transform and then accounts for both the multiscale correlation of the subband decompositions and their heavy-tailed statistics. Real microarray images have been processed by the proposed method and its improved performance is shown through quantitative measures and qualitative visual evaluation.

Original languageEnglish
Title of host publicationProceedings - 2007 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2007
Pages383-389
Number of pages7
DOIs
Publication statusPublished - 2007
Externally publishedYes
Event2007 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2007 - Fremont, CA, United States
Duration: 2 Nov 20074 Nov 2007

Publication series

NameProceedings - 2007 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2007

Conference

Conference2007 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2007
Country/TerritoryUnited States
CityFremont, CA
Period2/11/074/11/07

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