Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T): Early detection is of vital importance

M. N. Van Der Horst; J. H. Sillevis Smitt; M. A.D. Peters; M. A. Middelkamp Hup; L. Van Den Berg; R. Wösten-Van Asperen; A. Kindermann; J. H.M. Merks

Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T): Early detection is of vital importance

M. N. Van Der Horst
, J. H. Sillevis Smitt
, M. A.D. Peters
, M. A. Middelkamp Hup
, L. Van Den Berg
, R. Wösten-Van Asperen
, A. Kindermann
, J. H.M. Merks

Research output: Contribution to journal › Article › peer-review

Abstract

Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T) is an extremely rare disease and manifests itself with diffuse vascular cutaneous and gastrointestinal tract lesions, which can cause severe bleeding. The thrombocytopenia is chronic and fluctuating and thought to result from platelet trapping by the multifocal vascular lesions. We describe a newborn with numerous cutaneous and extracutaneous lesions who was successfully treated with thalidomide.

Translated title of the contribution	Multifocale lymphangio-endotheliomatose met trombocytopenie (MLE-T): vroegtijdige herkenning is van levensbelang
Original language	English
Pages (from-to)	314-317
Number of pages	4
Journal	Nederlands Tijdschrift voor Dermatologie en Venereologie
Volume	26
Issue number	5
Publication status	Published - 1 May 2016
Externally published	Yes

Keywords

Congenital vascular disease
Diffuse neonatal hemangiomatosis
MLE-T
MLT
Multifocal lymphangio-endotheliomatosis and thrombocytopenia
Thalidomide

Cite this

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title = "Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T): Early detection is of vital importance",

abstract = "Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T) is an extremely rare disease and manifests itself with diffuse vascular cutaneous and gastrointestinal tract lesions, which can cause severe bleeding. The thrombocytopenia is chronic and fluctuating and thought to result from platelet trapping by the multifocal vascular lesions. We describe a newborn with numerous cutaneous and extracutaneous lesions who was successfully treated with thalidomide.",

keywords = "Congenital vascular disease, Diffuse neonatal hemangiomatosis, MLE-T, MLT, Multifocal lymphangio-endotheliomatosis and thrombocytopenia, Thalidomide",

author = "\{Van Der Horst\}, \{M. N.\} and \{Sillevis Smitt\}, \{J. H.\} and Peters, \{M. A.D.\} and \{Middelkamp Hup\}, \{M. A.\} and \{Van Den Berg\}, L. and \{W{\"o}sten-Van Asperen\}, R. and A. Kindermann and Merks, \{J. H.M.\}",

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pages = "314--317",

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TY - JOUR

T1 - Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T)

T2 - Early detection is of vital importance

AU - Van Der Horst, M. N.

AU - Sillevis Smitt, J. H.

AU - Peters, M. A.D.

AU - Middelkamp Hup, M. A.

AU - Van Den Berg, L.

AU - Wösten-Van Asperen, R.

AU - Kindermann, A.

AU - Merks, J. H.M.

PY - 2016/5/1

Y1 - 2016/5/1

N2 - Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T) is an extremely rare disease and manifests itself with diffuse vascular cutaneous and gastrointestinal tract lesions, which can cause severe bleeding. The thrombocytopenia is chronic and fluctuating and thought to result from platelet trapping by the multifocal vascular lesions. We describe a newborn with numerous cutaneous and extracutaneous lesions who was successfully treated with thalidomide.

AB - Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T) is an extremely rare disease and manifests itself with diffuse vascular cutaneous and gastrointestinal tract lesions, which can cause severe bleeding. The thrombocytopenia is chronic and fluctuating and thought to result from platelet trapping by the multifocal vascular lesions. We describe a newborn with numerous cutaneous and extracutaneous lesions who was successfully treated with thalidomide.

KW - Congenital vascular disease

KW - Diffuse neonatal hemangiomatosis

KW - MLE-T

KW - MLT

KW - Multifocal lymphangio-endotheliomatosis and thrombocytopenia

KW - Thalidomide

UR - https://www.scopus.com/pages/publications/85029509659

M3 - Article

AN - SCOPUS:85029509659

SN - 0925-8604

VL - 26

SP - 314

EP - 317

JO - Nederlands Tijdschrift voor Dermatologie en Venereologie

JF - Nederlands Tijdschrift voor Dermatologie en Venereologie

IS - 5

ER -

Multifocal lymphangio-endotheliomatosis with thrombocytopenia (MLE-T): Early detection is of vital importance

Abstract

Keywords

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