Orbital rhabdomyosarcomas: A review

Lama Jurdy; Johanus H M Merks; Bradly R Pieters; Maarten P Mourits; Roel J H M Kloos; Simone D Strackee; Peerooz Saeed

doi:10.1016/j.sjopt.2013.06.004

Orbital rhabdomyosarcomas: A review

Lama Jurdy, Johanus H M Merks, Bradly R Pieters, Maarten P Mourits, Roel J H M Kloos, Simone D Strackee, Peerooz Saeed

Research output: Contribution to journal › Article › peer-review

49 Citations (Scopus)

Abstract

Rhabdomyosarcoma (RMS) is a highly malignant tumor and is one of the few life-threatening diseases that present first to the ophthalmologist. It is the most common soft-tissue sarcoma of the head and neck in childhood with 10% of all cases occurring in the orbit. RMS has been reported from birth to the seventh decade, with the majority of cases presenting in early childhood. Survival has changed drastically over the years, from 30% in the 1960's to 90% presently, with the advent of new diagnostic and therapeutic modalities. The purpose of this review is to provide a general overview of primary orbital RMS derived from a literature search of material published over the last 10 years, as well as to present two representative cases of patients that have been managed at our institute.

Original language	English
Pages (from-to)	167-75
Number of pages	9
Journal	Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society
Volume	27
Issue number	3
DOIs	https://doi.org/10.1016/j.sjopt.2013.06.004
Publication status	Published - Jul 2013
Externally published	Yes

Keywords

AMORE
Brachytherapy
Eye
Genetics
Orbit
Pediatrics
Rhabdomyosarcoma
Tumor

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10.1016/j.sjopt.2013.06.004

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title = "Orbital rhabdomyosarcomas: A review",

abstract = "Rhabdomyosarcoma (RMS) is a highly malignant tumor and is one of the few life-threatening diseases that present first to the ophthalmologist. It is the most common soft-tissue sarcoma of the head and neck in childhood with 10% of all cases occurring in the orbit. RMS has been reported from birth to the seventh decade, with the majority of cases presenting in early childhood. Survival has changed drastically over the years, from 30% in the 1960's to 90% presently, with the advent of new diagnostic and therapeutic modalities. The purpose of this review is to provide a general overview of primary orbital RMS derived from a literature search of material published over the last 10 years, as well as to present two representative cases of patients that have been managed at our institute. ",

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AU - Pieters, Bradly R

AU - Mourits, Maarten P

AU - Kloos, Roel J H M

AU - Strackee, Simone D

AU - Saeed, Peerooz

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Orbital rhabdomyosarcomas: A review

Abstract

Keywords

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