Ploidy of testicular carcinoma in situ

W. E. De Graaff; J. W. Oosterhuis; B. De Jong; A. Dam; W. L.J. Van Putten; S. M.M.J. Castedo; D. T. Sleijfer; H. S. Koops

Ploidy of testicular carcinoma in situ

W. E. De Graaff
, J. W. Oosterhuis
, B. De Jong
, A. Dam
, W. L.J. Van Putten
, S. M.M.J. Castedo
, D. T. Sleijfer
, H. S. Koops

Research output: Contribution to journal › Article › peer-review

77 Citations (Scopus)

Abstract

The ploidy of carcinoma in situ and invasive germ cell tumors of the adult testis was compared by DNA flow cytometry. Irrespective of the tumor type with which it was associated, the median DNA index of carcinoma in situ was about the same as that of seminomas and higher than the DNA index of invasive nonseminomatous germ cell tumors. These data indicate that seminoma and carcinoma in situ cells are not only phenotypically similar but also have the same ploidy.

Original language	English
Pages (from-to)	166-168
Number of pages	3
Journal	Laboratory Investigation
Volume	66
Issue number	2
Publication status	Published - 1992
Externally published	Yes

Keywords

Germ cell tumors
Nonseminoma
Seminoma

Cite this

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title = "Ploidy of testicular carcinoma in situ",

abstract = "The ploidy of carcinoma in situ and invasive germ cell tumors of the adult testis was compared by DNA flow cytometry. Irrespective of the tumor type with which it was associated, the median DNA index of carcinoma in situ was about the same as that of seminomas and higher than the DNA index of invasive nonseminomatous germ cell tumors. These data indicate that seminoma and carcinoma in situ cells are not only phenotypically similar but also have the same ploidy.",

keywords = "Germ cell tumors, Nonseminoma, Seminoma",

author = "\{De Graaff\}, \{W. E.\} and Oosterhuis, \{J. W.\} and \{De Jong\}, B. and A. Dam and \{Van Putten\}, \{W. L.J.\} and Castedo, \{S. M.M.J.\} and Sleijfer, \{D. T.\} and Koops, \{H. S.\}",

year = "1992",

language = "English",

volume = "66",

pages = "166--168",

journal = "Laboratory Investigation",

issn = "0023-6837",

publisher = "Elsevier B.V.",

number = "2",

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TY - JOUR

T1 - Ploidy of testicular carcinoma in situ

AU - De Graaff, W. E.

AU - Oosterhuis, J. W.

AU - De Jong, B.

AU - Dam, A.

AU - Van Putten, W. L.J.

AU - Castedo, S. M.M.J.

AU - Sleijfer, D. T.

AU - Koops, H. S.

PY - 1992

Y1 - 1992

N2 - The ploidy of carcinoma in situ and invasive germ cell tumors of the adult testis was compared by DNA flow cytometry. Irrespective of the tumor type with which it was associated, the median DNA index of carcinoma in situ was about the same as that of seminomas and higher than the DNA index of invasive nonseminomatous germ cell tumors. These data indicate that seminoma and carcinoma in situ cells are not only phenotypically similar but also have the same ploidy.

AB - The ploidy of carcinoma in situ and invasive germ cell tumors of the adult testis was compared by DNA flow cytometry. Irrespective of the tumor type with which it was associated, the median DNA index of carcinoma in situ was about the same as that of seminomas and higher than the DNA index of invasive nonseminomatous germ cell tumors. These data indicate that seminoma and carcinoma in situ cells are not only phenotypically similar but also have the same ploidy.

KW - Germ cell tumors

KW - Nonseminoma

KW - Seminoma

UR - https://www.scopus.com/pages/publications/0026583399

M3 - Article

C2 - 1310514

AN - SCOPUS:0026583399

SN - 0023-6837

VL - 66

SP - 166

EP - 168

JO - Laboratory Investigation

JF - Laboratory Investigation

IS - 2

ER -

Ploidy of testicular carcinoma in situ

Abstract

Keywords

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