Prevention and treatment of anticipatory chemotherapy-induced nausea and vomiting in pediatric cancer patients and hematopoietic stem cell recipients: Clinical practice guideline update

Priya Patel, Paula D. Robinson, Katie A. Devine, Karyn Positano, Marie Cohen, Paul Gibson, Mark Holdsworth, Robert Phillips, Daniela Spinelli, Jennifer Thackray, Marianne van de Wetering, Deborah Woods, Sandra Cabral, Lillian Sung, L. Lee Dupuis

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

This 2021 clinical practice guideline update provides recommendations for preventing anticipatory chemotherapy-induced nausea and vomiting (CINV) in pediatric patients. Recommendations are based on systematic reviews that identified (1) if a history of acute or delayed CINV is a risk factor for anticipatory CINV, and (2) interventions for anticipatory CINV prevention and treatment. A strong recommendation to optimize acute and delayed CINV control in order to prevent anticipatory CINV is made. Conditional recommendations are made for hypnosis, systematic desensitization, relaxation techniques, and lorazepam for the secondary prevention of anticipatory CINV. No recommendation for the treatment of anticipatory CINV can be made.

Original languageEnglish
Article numbere28947
JournalPediatric Blood and Cancer
Volume68
Issue number5
DOIs
Publication statusPublished - May 2021

Keywords

  • anticipatory
  • chemotherapy-induced nausea and vomiting
  • pediatric oncology
  • supportive care

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