Reconstructing single-cell karyotype alterations in colorectal cancer identifies punctuated and gradual diversification patterns

Yannik Bollen, Ellen Stelloo, Petra van Leenen, Myrna van den Bos, Bas Ponsioen, Bingxin Lu, Markus J. van Roosmalen, Ana C.F. Bolhaqueiro, Christopher Kimberley, Maximilian Mossner, William C.H. Cross, Nicolle J.M. Besselink, Bastiaan van der Roest, Sander Boymans, Koen C. Oost, Sippe G. de Vries, Holger Rehmann, Edwin Cuppen, Susanne M.A. Lens, Geert J.P.L. KopsWigard P. Kloosterman, Leon W.M.M. Terstappen, Chris P. Barnes, Andrea Sottoriva, Trevor A. Graham, Hugo J.G. Snippert

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Medicine and Dentistry

Biochemistry, Genetics and Molecular Biology