Successful treatment of Fusarium keratitis with cornea transplantation and topical and systemic voriconazole.

Rocus R. Klont; Cathrien A. Eggink; Antonius J.M.M. Rijs; Pieter Wesseling; Paul E. Verweij

doi:10.1086/430062

Successful treatment of Fusarium keratitis with cornea transplantation and topical and systemic voriconazole.

Rocus R. Klont
, Cathrien A. Eggink
, Antonius J.M.M. Rijs
, Pieter Wesseling
, Paul E. Verweij

Research output: Contribution to journal › Article › peer-review

80 Citations (Scopus)

Abstract

A case of invasive Fusarium keratitis in a previously healthy male patient was treated successfully with cornea transplantation and systemic and topical voriconazole after treatment failure with topical amphotericin B and systemic itraconazole. Topical voriconazole was well tolerated, and, in conjunction with the oral administration, it resulted in a high level of the drug in the anterior chamber of the eye (which was 160% of the plasma drug level).

Original language	English
Pages (from-to)	e110-112
Journal	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume	40
Issue number	12
DOIs	https://doi.org/10.1086/430062
Publication status	Published - 15 Jun 2005
Externally published	Yes

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10.1086/430062

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title = "Successful treatment of Fusarium keratitis with cornea transplantation and topical and systemic voriconazole.",

abstract = "A case of invasive Fusarium keratitis in a previously healthy male patient was treated successfully with cornea transplantation and systemic and topical voriconazole after treatment failure with topical amphotericin B and systemic itraconazole. Topical voriconazole was well tolerated, and, in conjunction with the oral administration, it resulted in a high level of the drug in the anterior chamber of the eye (which was 160\% of the plasma drug level).",

author = "Klont, \{Rocus R.\} and Eggink, \{Cathrien A.\} and Rijs, \{Antonius J.M.M.\} and Pieter Wesseling and Verweij, \{Paul E.\}",

year = "2005",

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volume = "40",

pages = "e110--112",

journal = "Clinical infectious diseases : an official publication of the Infectious Diseases Society of America",

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Successful treatment of Fusarium keratitis with cornea transplantation and topical and systemic voriconazole. / Klont, Rocus R.; Eggink, Cathrien A.; Rijs, Antonius J.M.M. et al.
In: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol. 40, No. 12, 15.06.2005, p. e110-112.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Successful treatment of Fusarium keratitis with cornea transplantation and topical and systemic voriconazole.

AU - Klont, Rocus R.

AU - Eggink, Cathrien A.

AU - Rijs, Antonius J.M.M.

AU - Wesseling, Pieter

AU - Verweij, Paul E.

PY - 2005/6/15

Y1 - 2005/6/15

N2 - A case of invasive Fusarium keratitis in a previously healthy male patient was treated successfully with cornea transplantation and systemic and topical voriconazole after treatment failure with topical amphotericin B and systemic itraconazole. Topical voriconazole was well tolerated, and, in conjunction with the oral administration, it resulted in a high level of the drug in the anterior chamber of the eye (which was 160% of the plasma drug level).

AB - A case of invasive Fusarium keratitis in a previously healthy male patient was treated successfully with cornea transplantation and systemic and topical voriconazole after treatment failure with topical amphotericin B and systemic itraconazole. Topical voriconazole was well tolerated, and, in conjunction with the oral administration, it resulted in a high level of the drug in the anterior chamber of the eye (which was 160% of the plasma drug level).

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DO - 10.1086/430062

M3 - Article

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JO - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

IS - 12

ER -

Successful treatment of Fusarium keratitis with cornea transplantation and topical and systemic voriconazole.

Abstract

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