Successful use of indwelling tunneled catheters for the management of effusions in children with advanced cancer

Barbara S. Den Hollander; Bairbre L. Connolly; Lillian Sung; Adam Rapoport; C. M. Zwaan; Ronald M. Grant; Dimitri Parra; Michael J. Temple

doi:10.1002/pbc.24902

Successful use of indwelling tunneled catheters for the management of effusions in children with advanced cancer

Barbara S. Den Hollander, Bairbre L. Connolly, Lillian Sung, Adam Rapoport, C. M. Zwaan, Ronald M. Grant, Dimitri Parra, Michael J. Temple

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Background: Malignant pleural effusion (MPE) and ascites (MA) negatively impact quality of life of palliative patients. Treatment options are limited. This study's purpose is to examine the experience with indwelling tunneled catheters (ITCs) for management of MPE/MA in children with advanced cancer. Methods: Children with MPE/MA who underwent ITC insertion (2007-2012) were retrospectively reviewed. Clinical, procedural, complication and outcome details were analyzed. Results: PleurX® ITCs (n=12) were inserted in eight patients (5-18 years) with sarcoma (11 MPE, 1 MA), achieving symptom relief and facilitating discharge home post ITC (median 2 days). Median survival following ITC was 51 days. There were two major complications: pain (n=1), late site infection (n=1), and five minor complications. Drainage ceased in four patients (pleurodesis/tumor progression). At time of death, six ITCs (five patients) were still in situ. Conclusions: ITC appears to be a safe, effective treatment for MPE/MA in advanced pediatric cancer, achieving symptomatic relief and discharge home. Pediatr Blood Cancer 2014;61:1007-1012.

Original language	English
Pages (from-to)	1007-1012
Number of pages	6
Journal	Pediatric Blood and Cancer
Volume	61
Issue number	6
DOIs	https://doi.org/10.1002/pbc.24902
Publication status	Published - Jun 2014
Externally published	Yes

Keywords

Ascites
Catheters
Indwelling
Malignant
Pediatric oncology
Pleural effusion

Access to Document

10.1002/pbc.24902

Cite this

@article{47bb61e0eeea4e129bba5e485fc78a7a,

title = "Successful use of indwelling tunneled catheters for the management of effusions in children with advanced cancer",

abstract = "Background: Malignant pleural effusion (MPE) and ascites (MA) negatively impact quality of life of palliative patients. Treatment options are limited. This study's purpose is to examine the experience with indwelling tunneled catheters (ITCs) for management of MPE/MA in children with advanced cancer. Methods: Children with MPE/MA who underwent ITC insertion (2007-2012) were retrospectively reviewed. Clinical, procedural, complication and outcome details were analyzed. Results: PleurX{\textregistered} ITCs (n=12) were inserted in eight patients (5-18 years) with sarcoma (11 MPE, 1 MA), achieving symptom relief and facilitating discharge home post ITC (median 2 days). Median survival following ITC was 51 days. There were two major complications: pain (n=1), late site infection (n=1), and five minor complications. Drainage ceased in four patients (pleurodesis/tumor progression). At time of death, six ITCs (five patients) were still in situ. Conclusions: ITC appears to be a safe, effective treatment for MPE/MA in advanced pediatric cancer, achieving symptomatic relief and discharge home. Pediatr Blood Cancer 2014;61:1007-1012.",

keywords = "Ascites, Catheters, Indwelling, Malignant, Pediatric oncology, Pleural effusion",

author = "{Den Hollander}, {Barbara S.} and Connolly, {Bairbre L.} and Lillian Sung and Adam Rapoport and Zwaan, {C. M.} and Grant, {Ronald M.} and Dimitri Parra and Temple, {Michael J.}",

year = "2014",

month = jun,

doi = "10.1002/pbc.24902",

language = "English",

volume = "61",

pages = "1007--1012",

journal = "Pediatric Blood and Cancer",

issn = "1545-5009",

publisher = "Wiley-Liss Inc.",

number = "6",

}

TY - JOUR

T1 - Successful use of indwelling tunneled catheters for the management of effusions in children with advanced cancer

AU - Den Hollander, Barbara S.

AU - Connolly, Bairbre L.

AU - Sung, Lillian

AU - Rapoport, Adam

AU - Zwaan, C. M.

AU - Grant, Ronald M.

AU - Parra, Dimitri

AU - Temple, Michael J.

PY - 2014/6

Y1 - 2014/6

N2 - Background: Malignant pleural effusion (MPE) and ascites (MA) negatively impact quality of life of palliative patients. Treatment options are limited. This study's purpose is to examine the experience with indwelling tunneled catheters (ITCs) for management of MPE/MA in children with advanced cancer. Methods: Children with MPE/MA who underwent ITC insertion (2007-2012) were retrospectively reviewed. Clinical, procedural, complication and outcome details were analyzed. Results: PleurX® ITCs (n=12) were inserted in eight patients (5-18 years) with sarcoma (11 MPE, 1 MA), achieving symptom relief and facilitating discharge home post ITC (median 2 days). Median survival following ITC was 51 days. There were two major complications: pain (n=1), late site infection (n=1), and five minor complications. Drainage ceased in four patients (pleurodesis/tumor progression). At time of death, six ITCs (five patients) were still in situ. Conclusions: ITC appears to be a safe, effective treatment for MPE/MA in advanced pediatric cancer, achieving symptomatic relief and discharge home. Pediatr Blood Cancer 2014;61:1007-1012.

AB - Background: Malignant pleural effusion (MPE) and ascites (MA) negatively impact quality of life of palliative patients. Treatment options are limited. This study's purpose is to examine the experience with indwelling tunneled catheters (ITCs) for management of MPE/MA in children with advanced cancer. Methods: Children with MPE/MA who underwent ITC insertion (2007-2012) were retrospectively reviewed. Clinical, procedural, complication and outcome details were analyzed. Results: PleurX® ITCs (n=12) were inserted in eight patients (5-18 years) with sarcoma (11 MPE, 1 MA), achieving symptom relief and facilitating discharge home post ITC (median 2 days). Median survival following ITC was 51 days. There were two major complications: pain (n=1), late site infection (n=1), and five minor complications. Drainage ceased in four patients (pleurodesis/tumor progression). At time of death, six ITCs (five patients) were still in situ. Conclusions: ITC appears to be a safe, effective treatment for MPE/MA in advanced pediatric cancer, achieving symptomatic relief and discharge home. Pediatr Blood Cancer 2014;61:1007-1012.

KW - Ascites

KW - Catheters

KW - Indwelling

KW - Malignant

KW - Pediatric oncology

KW - Pleural effusion

UR - http://www.scopus.com/inward/record.url?scp=84901702129&partnerID=8YFLogxK

U2 - 10.1002/pbc.24902

DO - 10.1002/pbc.24902

M3 - Article

C2 - 24376007

AN - SCOPUS:84901702129

SN - 1545-5009

VL - 61

SP - 1007

EP - 1012

JO - Pediatric Blood and Cancer

JF - Pediatric Blood and Cancer

IS - 6

ER -

Successful use of indwelling tunneled catheters for the management of effusions in children with advanced cancer

Abstract

Keywords

Access to Document

Fingerprint

Cite this