Tales of the Unexpected: Tcf1 Functions as a Tumor Suppressor for Leukemias

Frank J.T. Staal; Hans Clevers

doi:10.1016/j.immuni.2012.10.008

Tales of the Unexpected: Tcf1 Functions as a Tumor Suppressor for Leukemias

Frank J.T. Staal
, Hans Clevers

Research output: Contribution to journal › Short survey › peer-review

8 Citations (Scopus)

Abstract

The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.

Original language	English
Pages (from-to)	761-763
Number of pages	3
Journal	Immunity
Volume	37
Issue number	5
DOIs	https://doi.org/10.1016/j.immuni.2012.10.008
Publication status	Published - 16 Nov 2012
Externally published	Yes

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10.1016/j.immuni.2012.10.008

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title = "Tales of the Unexpected: Tcf1 Functions as a Tumor Suppressor for Leukemias",

abstract = "The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.",

author = "Staal, \{Frank J.T.\} and Hans Clevers",

year = "2012",

month = nov,

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doi = "10.1016/j.immuni.2012.10.008",

language = "English",

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pages = "761--763",

journal = "Immunity",

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TY - JOUR

T1 - Tales of the Unexpected

T2 - Tcf1 Functions as a Tumor Suppressor for Leukemias

AU - Staal, Frank J.T.

AU - Clevers, Hans

PY - 2012/11/16

Y1 - 2012/11/16

N2 - The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.

AB - The Wnt-responsive transcription factors Tcf1 and Lef1 are well-known for their roles in lymphocyte development. In this issue of Immunity, Yu et al. (2012) report that Tcf1-deficient mice develop aggressive T cell lymphomas that are characterized by high Lef1 expression.

UR - https://www.scopus.com/pages/publications/84869234417

U2 - 10.1016/j.immuni.2012.10.008

DO - 10.1016/j.immuni.2012.10.008

M3 - Short survey

AN - SCOPUS:84869234417

SN - 1074-7613

VL - 37

SP - 761

EP - 763

JO - Immunity

JF - Immunity

IS - 5

ER -

Tales of the Unexpected: Tcf1 Functions as a Tumor Suppressor for Leukemias

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