The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

Anna Wojtuszkiewicz; Yehuda G. Assaraf; Mirthe Hoekstra; Rocco Sciarrillo; Gerrit Jansen; Godefridus J. Peters; Rob Pieters; Edwin Sonneveld; Gabriele Escherich; Gertjan J.L. Kaspers; Jacqueline Cloos

doi:10.3324/haematol.2016.142794

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

Anna Wojtuszkiewicz, Yehuda G. Assaraf, Mirthe Hoekstra, Rocco Sciarrillo, Gerrit Jansen, Godefridus J. Peters, Rob Pieters, Edwin Sonneveld, Gabriele Escherich, Gertjan J.L. Kaspers, Jacqueline Cloos

Group Pieters

Research output: Contribution to journal › Letter › peer-review

16 Citations (Scopus)

Original language	English
Pages (from-to)	e291-e294
Journal	Haematologica
Volume	101
Issue number	7
DOIs	https://doi.org/10.3324/haematol.2016.142794
Publication status	Published - 2016

Keywords

Aberrant splicing
Dexamethasone
Folylpolyglutamate synthetase
Methotrexate
Pediatric acute lymphoblastic leukemia

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10.3324/haematol.2016.142794

Cite this

Wojtuszkiewicz, A., Assaraf, Y. G., Hoekstra, M., Sciarrillo, R., Jansen, G., Peters, G. J., Pieters, R., Sonneveld, E., Escherich, G., Kaspers, G. J. L., & Cloos, J. (2016). The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia. Haematologica, 101(7), e291-e294. https://doi.org/10.3324/haematol.2016.142794

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title = "The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia",

keywords = "Aberrant splicing, Dexamethasone, Folylpolyglutamate synthetase, Methotrexate, Pediatric acute lymphoblastic leukemia",

author = "Anna Wojtuszkiewicz and Assaraf, {Yehuda G.} and Mirthe Hoekstra and Rocco Sciarrillo and Gerrit Jansen and Peters, {Godefridus J.} and Rob Pieters and Edwin Sonneveld and Gabriele Escherich and Kaspers, {Gertjan J.L.} and Jacqueline Cloos",

year = "2016",

doi = "10.3324/haematol.2016.142794",

language = "English",

volume = "101",

pages = "e291--e294",

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Wojtuszkiewicz, A, Assaraf, YG, Hoekstra, M, Sciarrillo, R, Jansen, G, Peters, GJ, Pieters, R, Sonneveld, E, Escherich, G, Kaspers, GJL & Cloos, J 2016, 'The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia', Haematologica, vol. 101, no. 7, pp. e291-e294. https://doi.org/10.3324/haematol.2016.142794

TY - JOUR

T1 - The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

AU - Wojtuszkiewicz, Anna

AU - Assaraf, Yehuda G.

AU - Hoekstra, Mirthe

AU - Sciarrillo, Rocco

AU - Jansen, Gerrit

AU - Peters, Godefridus J.

AU - Pieters, Rob

AU - Sonneveld, Edwin

AU - Escherich, Gabriele

AU - Kaspers, Gertjan J.L.

AU - Cloos, Jacqueline

PY - 2016

Y1 - 2016

KW - Aberrant splicing

KW - Dexamethasone

KW - Folylpolyglutamate synthetase

KW - Methotrexate

KW - Pediatric acute lymphoblastic leukemia

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U2 - 10.3324/haematol.2016.142794

DO - 10.3324/haematol.2016.142794

M3 - Letter

C2 - 27036162

AN - SCOPUS:84977120405

SN - 0390-6078

VL - 101

SP - e291-e294

JO - Haematologica

JF - Haematologica

IS - 7

ER -