The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

Anna Wojtuszkiewicz; Yehuda G. Assaraf; Mirthe Hoekstra; Rocco Sciarrillo; Gerrit Jansen; Godefridus J. Peters; Rob Pieters; Edwin Sonneveld; Gabriele Escherich; Gertjan J.L. Kaspers; Jacqueline Cloos

doi:10.3324/haematol.2016.142794

The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

Anna Wojtuszkiewicz
, Yehuda G. Assaraf
, Mirthe Hoekstra
, Rocco Sciarrillo
, Gerrit Jansen
, Godefridus J. Peters
, Rob Pieters
, Edwin Sonneveld
, Gabriele Escherich
, Gertjan J.L. Kaspers
, Jacqueline Cloos

Group Pieters

Research output: Contribution to journal › Letter › peer-review

19 Citations (Scopus)

Original language	English
Pages (from-to)	e291-e294
Journal	Haematologica
Volume	101
Issue number	7
DOIs	https://doi.org/10.3324/haematol.2016.142794
Publication status	Published - 2016

Keywords

Aberrant splicing
Dexamethasone
Folylpolyglutamate synthetase
Methotrexate
Pediatric acute lymphoblastic leukemia

Access to Document

10.3324/haematol.2016.142794

Cite this

Wojtuszkiewicz, A., Assaraf, Y. G., Hoekstra, M., Sciarrillo, R., Jansen, G., Peters, G. J., Pieters, R., Sonneveld, E., Escherich, G., Kaspers, G. J. L., & Cloos, J. (2016). The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia. Haematologica, 101(7), e291-e294. https://doi.org/10.3324/haematol.2016.142794

@article{8421d84ef8e64bc4bea017550f6bc946,

title = "The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia",

keywords = "Aberrant splicing, Dexamethasone, Folylpolyglutamate synthetase, Methotrexate, Pediatric acute lymphoblastic leukemia",

author = "Anna Wojtuszkiewicz and Assaraf, \{Yehuda G.\} and Mirthe Hoekstra and Rocco Sciarrillo and Gerrit Jansen and Peters, \{Godefridus J.\} and Rob Pieters and Edwin Sonneveld and Gabriele Escherich and Kaspers, \{Gertjan J.L.\} and Jacqueline Cloos",

year = "2016",

doi = "10.3324/haematol.2016.142794",

language = "English",

volume = "101",

pages = "e291--e294",

journal = "Haematologica",

issn = "0390-6078",

publisher = "Ferrata Storti Foundation",

number = "7",

}

Wojtuszkiewicz, A, Assaraf, YG, Hoekstra, M, Sciarrillo, R, Jansen, G, Peters, GJ, Pieters, R, Sonneveld, E, Escherich, G, Kaspers, GJL & Cloos, J 2016, 'The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia', Haematologica, vol. 101, no. 7, pp. e291-e294. https://doi.org/10.3324/haematol.2016.142794

TY - JOUR

T1 - The association of aberrant folylpolyglutamate synthetase splicing with ex vivo methotrexate resistance and clinical outcome in childhood acute lymphoblastic leukemia

AU - Wojtuszkiewicz, Anna

AU - Assaraf, Yehuda G.

AU - Hoekstra, Mirthe

AU - Sciarrillo, Rocco

AU - Jansen, Gerrit

AU - Peters, Godefridus J.

AU - Pieters, Rob

AU - Sonneveld, Edwin

AU - Escherich, Gabriele

AU - Kaspers, Gertjan J.L.

AU - Cloos, Jacqueline

PY - 2016

Y1 - 2016

KW - Aberrant splicing

KW - Dexamethasone

KW - Folylpolyglutamate synthetase

KW - Methotrexate

KW - Pediatric acute lymphoblastic leukemia

UR - https://www.scopus.com/pages/publications/84977120405

U2 - 10.3324/haematol.2016.142794

DO - 10.3324/haematol.2016.142794

M3 - Letter

C2 - 27036162

AN - SCOPUS:84977120405

SN - 0390-6078

VL - 101

SP - e291-e294

JO - Haematologica

JF - Haematologica

IS - 7

ER -