The short- and long-term effect of single high-dose intra-operative electron beam irradiation of retroperitoneal structures - An experimental study in dogs

H. J. Hoekstra; D. M. Mehta; J. W. Oosterhuis; P. Westra; J. Van den Dungen; R. G. Dijkstra

The short- and long-term effect of single high-dose intra-operative electron beam irradiation of retroperitoneal structures - An experimental study in dogs

H. J. Hoekstra
, D. M. Mehta
, J. W. Oosterhuis
, P. Westra
, J. Van den Dungen
, R. G. Dijkstra

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

Intra-operative electron beam radiotherapy is a new treatment modality. The abdomen is the area of greatest potential applicability of IORT and therefore its effect on retroperitoneal structures was investigated in a canine model. The retroperitoneal structures tolerate 30 to 40 Gy well, with the exception of the radiation-sensitive ureter which showed fibrosis. Twenty to 25 Gy is within the safe dose limits for the clinical application of IORT.

Original language	English
Pages (from-to)	240-247
Number of pages	8
Journal	European Journal of Surgical Oncology
Volume	16
Issue number	3
Publication status	Published - 1990
Externally published	Yes

Keywords

intra-operative, radiation, retroperitoneal, ureter

Cite this

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title = "The short- and long-term effect of single high-dose intra-operative electron beam irradiation of retroperitoneal structures - An experimental study in dogs",

abstract = "Intra-operative electron beam radiotherapy is a new treatment modality. The abdomen is the area of greatest potential applicability of IORT and therefore its effect on retroperitoneal structures was investigated in a canine model. The retroperitoneal structures tolerate 30 to 40 Gy well, with the exception of the radiation-sensitive ureter which showed fibrosis. Twenty to 25 Gy is within the safe dose limits for the clinical application of IORT.",

keywords = "intra-operative, radiation, retroperitoneal, ureter",

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year = "1990",

language = "English",

volume = "16",

pages = "240--247",

journal = "European Journal of Surgical Oncology",

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T1 - The short- and long-term effect of single high-dose intra-operative electron beam irradiation of retroperitoneal structures - An experimental study in dogs

AU - Hoekstra, H. J.

AU - Mehta, D. M.

AU - Oosterhuis, J. W.

AU - Westra, P.

AU - Van den Dungen, J.

AU - Dijkstra, R. G.

PY - 1990

Y1 - 1990

N2 - Intra-operative electron beam radiotherapy is a new treatment modality. The abdomen is the area of greatest potential applicability of IORT and therefore its effect on retroperitoneal structures was investigated in a canine model. The retroperitoneal structures tolerate 30 to 40 Gy well, with the exception of the radiation-sensitive ureter which showed fibrosis. Twenty to 25 Gy is within the safe dose limits for the clinical application of IORT.

AB - Intra-operative electron beam radiotherapy is a new treatment modality. The abdomen is the area of greatest potential applicability of IORT and therefore its effect on retroperitoneal structures was investigated in a canine model. The retroperitoneal structures tolerate 30 to 40 Gy well, with the exception of the radiation-sensitive ureter which showed fibrosis. Twenty to 25 Gy is within the safe dose limits for the clinical application of IORT.

KW - intra-operative, radiation, retroperitoneal, ureter

UR - https://www.scopus.com/pages/publications/0025375908

M3 - Article

C2 - 2347417

AN - SCOPUS:0025375908

SN - 0748-7983

VL - 16

SP - 240

EP - 247

JO - European Journal of Surgical Oncology

JF - European Journal of Surgical Oncology

IS - 3

ER -

The short- and long-term effect of single high-dose intra-operative electron beam irradiation of retroperitoneal structures - An experimental study in dogs

Abstract

Keywords

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