Therapeutic total plasma exchange in a child with neuroblastoma-related anti-Hu syndrome

Dannis G van Vuurden; Frans B Plötz; Miranda de Jong; Arend Bokenkamp; Joanna A E van Wijk

doi:10.1007/s00467-005-2004-8

Therapeutic total plasma exchange in a child with neuroblastoma-related anti-Hu syndrome

Dannis G van Vuurden, Frans B Plötz, Miranda de Jong, Arend Bokenkamp, Joanna A E van Wijk

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

A 5-year-old boy underwent total plasma exchange to remove anti-neuronal anti-Hu autoantibodies as a complication of neuroblastoma, leading to autonomic bowel dysfunction. Total plasma exchange (TPE) resulted eventually in a reduction of autoantibody levels, but, more importantly, led to improvement of bowel function. TPE proved to be a safe and effective treatment option in neuroblastoma-related anti-Hu syndrome in a child.

Original language	English
Pages (from-to)	1655-6
Number of pages	2
Journal	Pediatric nephrology (Berlin, Germany)
Volume	20
Issue number	11
DOIs	https://doi.org/10.1007/s00467-005-2004-8
Publication status	Published - Nov 2005
Externally published	Yes

Keywords

Autoantibodies/blood
Child, Preschool
ELAV Proteins/immunology
Humans
Male
Neuroblastoma/immunology
Paraneoplastic Syndromes, Nervous System/immunology
Plasma Exchange
Spinal Cord Neoplasms/immunology

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10.1007/s00467-005-2004-8

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title = "Therapeutic total plasma exchange in a child with neuroblastoma-related anti-Hu syndrome",

abstract = "A 5-year-old boy underwent total plasma exchange to remove anti-neuronal anti-Hu autoantibodies as a complication of neuroblastoma, leading to autonomic bowel dysfunction. Total plasma exchange (TPE) resulted eventually in a reduction of autoantibody levels, but, more importantly, led to improvement of bowel function. TPE proved to be a safe and effective treatment option in neuroblastoma-related anti-Hu syndrome in a child.",

keywords = "Autoantibodies/blood, Child, Preschool, ELAV Proteins/immunology, Humans, Male, Neuroblastoma/immunology, Paraneoplastic Syndromes, Nervous System/immunology, Plasma Exchange, Spinal Cord Neoplasms/immunology",

author = "{van Vuurden}, {Dannis G} and Pl{\"o}tz, {Frans B} and {de Jong}, Miranda and Arend Bokenkamp and {van Wijk}, {Joanna A E}",

year = "2005",

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doi = "10.1007/s00467-005-2004-8",

language = "English",

volume = "20",

pages = "1655--6",

journal = "Pediatric nephrology (Berlin, Germany)",

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number = "11",

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T1 - Therapeutic total plasma exchange in a child with neuroblastoma-related anti-Hu syndrome

AU - van Vuurden, Dannis G

AU - Plötz, Frans B

AU - de Jong, Miranda

AU - Bokenkamp, Arend

AU - van Wijk, Joanna A E

PY - 2005/11

Y1 - 2005/11

N2 - A 5-year-old boy underwent total plasma exchange to remove anti-neuronal anti-Hu autoantibodies as a complication of neuroblastoma, leading to autonomic bowel dysfunction. Total plasma exchange (TPE) resulted eventually in a reduction of autoantibody levels, but, more importantly, led to improvement of bowel function. TPE proved to be a safe and effective treatment option in neuroblastoma-related anti-Hu syndrome in a child.

AB - A 5-year-old boy underwent total plasma exchange to remove anti-neuronal anti-Hu autoantibodies as a complication of neuroblastoma, leading to autonomic bowel dysfunction. Total plasma exchange (TPE) resulted eventually in a reduction of autoantibody levels, but, more importantly, led to improvement of bowel function. TPE proved to be a safe and effective treatment option in neuroblastoma-related anti-Hu syndrome in a child.

KW - Autoantibodies/blood

KW - Child, Preschool

KW - ELAV Proteins/immunology

KW - Humans

KW - Male

KW - Neuroblastoma/immunology

KW - Paraneoplastic Syndromes, Nervous System/immunology

KW - Plasma Exchange

KW - Spinal Cord Neoplasms/immunology

U2 - 10.1007/s00467-005-2004-8

DO - 10.1007/s00467-005-2004-8

M3 - Article

C2 - 16133055

SN - 0931-041X

VL - 20

SP - 1655

EP - 1656

JO - Pediatric nephrology (Berlin, Germany)

JF - Pediatric nephrology (Berlin, Germany)

IS - 11

ER -

Therapeutic total plasma exchange in a child with neuroblastoma-related anti-Hu syndrome

Abstract

Keywords

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